Chronic graft-versus-host disease (cGVHD) is one of the major causes of late mortality after allogenic hematopoietic stem cell transplantation. Moderate-to-severe cGVHD is associated …
PURPOSE Hematopoietic cell transplantation (HCT) is curative for hematologic disorders, but outcomes are historically inferior when using HLA-mismatched donors. Despite …
M Gooptu, R Romee, A St. Martin… - Blood, The Journal …, 2021 - ashpublications.org
Posttransplant cyclophosphamide (PTCy) graft-versus-host disease (GVHD) prophylaxis has enabled haploidentical (Haplo) transplantation to be performed with results similar to those …
A Ruggeri, M Labopin, A Bacigalupo… - Journal of hematology & …, 2018 - Springer
Background Experience using post-transplant cyclophosphamide (PT-Cy) as graft-versus- host disease (GVHD) prophylaxis in allogeneic stem cell transplantation (HSCT) from …
A Ruggeri, M Labopin, A Bacigalupo, Z Gülbas, Y Koc… - Cancer, 2018 - Wiley Online Library
BACKGROUND Incidence of graft‐versus‐host disease (GVHD) in haploidentical bone marrow (BM) transplants using posttransplantion cyclophosphamide (PT‐Cy) is low …
R Duléry, F Malard, E Brissot, A Banet… - Bone Marrow …, 2023 - nature.com
Post-transplant cyclophosphamide (PT-Cy) is effective for graft-versus-host disease (GVHD) prophylaxis, but it may cause dose-dependent toxicities, particularly in frail patients …
A Rashidi, M Hamadani, MJ Zhang, HL Wang… - Blood …, 2019 - ashpublications.org
HLA-haploidentical hematopoietic cell transplantation (Haplo-HCT) using posttransplantation cyclophosphamide (PT-Cy) has improved donor availability. However, a …
J Sanz, JE Galimard, M Labopin, B Afanasyev… - Journal of hematology & …, 2020 - Springer
Background The use of post-transplant cyclophosphamide (PTCy) is highly effective in preventing graft-versus-host disease (GVHD) in the haploidentical (Haplo) transplant setting …
In search of an ideal partner or alternative to conventional immunosuppressive agents, rabbit anti-thymocyte globulin (ATG) and, more recently, post-transplant cyclophosphamide …