The pathogenesis of mucositis: updated perspectives and emerging targets

J Bowen, N Al-Dasooqi, P Bossi, H Wardill… - Supportive Care in …, 2019 - Springer
Mucositis research and treatment are a rapidly evolving field providing constant new
avenues of research and potential therapies. The MASCC/ISOO Mucositis Study Group …

Oral mucositis due to high-dose chemotherapy and/or head and neck radiation therapy

RV Lalla, MT Brennan, SM Gordon, ST Sonis… - JNCI …, 2019 - academic.oup.com
Oral mucositis is a common side-effect associated with conventional cancer therapy and has
also recently been reported in association with newly emerging cancer therapies. It is …

Alteration of gut microbiota and inflammatory cytokine/chemokine profiles in 5-fluorouracil induced intestinal mucositis

HL Li, L Lu, XS Wang, LY Qin, P Wang… - Frontiers in cellular …, 2017 - frontiersin.org
Disturbed homeostasis of gut microbiota has been suggested to be closely associated with 5-
fluorouracil (5-Fu) induced mucositis. However, current knowledge of the overall profiles of 5 …

Metal complex strategies for photo-uncaging the small molecule bioregulators nitric oxide and carbon monoxide

PC Ford - Coordination Chemistry Reviews, 2018 - Elsevier
Photochemical release (uncaging) of small molecule bioregulators (SMBs) such as nitric
oxide (NO) or carbon monoxide (CO) at physiological sites offers exquisite control of timing …

Experimental chemotherapy-induced mucositis: a scoping review guiding the design of suitable preclinical models

J Huang, AYM Hwang, Y Jia, B Kim, M Iskandar… - International Journal of …, 2022 - mdpi.com
Mucositis is a common and most debilitating complication associated with the cytotoxicity of
chemotherapy. The condition affects the entire alimentary canal from the mouth to the anus …

5-fluorouracil induces enteric neuron death and glial activation during intestinal mucositis via a S100B-RAGE-NFκB-dependent pathway

DVS Costa, AC Bon-Frauches, AMHP Silva… - Scientific reports, 2019 - nature.com
Fluorouracil (5-FU) is an anticancer agent whose main side effects include intestinal
mucositis associated with intestinal motility alterations maybe due to an effect on the enteric …

Differential nanoreprotoxicity of silver nanoparticles in male somatic cells and spermatogonial stem cells

XF Zhang, YJ Choi, JW Han, E Kim… - International journal …, 2015 - Taylor & Francis
Background Silver nanoparticles (AgNPs) possess unique physical, chemical, and
biological properties. AgNPs have been increasingly used as anticancer, antiangiogenic …

[HTML][HTML] Assessment of dose-response relationship of 5-fluorouracil to murine intestinal injury

S Zhang, Y Liu, D Xiang, J Yang, D Liu, X Ren… - Biomedicine & …, 2018 - Elsevier
Fluorouracil (5-FU) is the most frequently prescribed anti-tumor drug, but has been reported
to result in intestinal injury. Although some progress has been made in understanding the …

Patchouli oil ameliorates 5-fluorouracil-induced intestinal mucositis in rats via protecting intestinal barrier and regulating water transport

Y Gan, G Ai, J Wu, H Luo, L Chen, Q Huang… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Pogostemon cablin, commonly named “Guang-Huo-
Xiang” in China, has long been renowned for its ability to dispel dampness and regulate …

A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines

Q Zhao, T Kim, J Pang, W Sun, X Yang… - Journal of leukocyte …, 2017 - academic.oup.com
Abstract IFN-γ–inducible protein 10 (CXCL10), a chemokine that is abundantly secreted in
response to inflammatory stimuli, has been implicated in the pathogenesis of multiple …