Disease progression of chronic obstructive pulmonary disease (COPD) is variable, with
some patients having a relatively stable course, while others suffer relentless progression …

Chronic obstructive pulmonary disease (COPD) is recognized as a disease of accelerated
lung aging. Over the past two decades, mounting evidence suggests an accumulation of …

Mutations in the essential telomerase genes TERT and TR cause familial pulmonary fibrosis;
however, in telomerase-null mice, short telomeres predispose to emphysema after chronic …

Epidemiological studies have reported inconsistent associations between telomere length
(TL) and risk for various cancers. These inconsistencies are likely attributable, in part, to …

Abstract Background Chronic Obstructive Pulmonary Disease (COPD) may be associated
with accelerated aging. Telomere shortening is a biomarker of aging. Cross-sectional …

Combination antiretroviral therapy (cART) has extended the longevity of human
immunodeficiency virus (HIV)-infected individuals. However, this has resulted in greater …

Background: Telomere length is a molecular marker of biological aging. Objective: Here we
investigated whether early-life exposure to residential air pollution was associated with …

Background Evidence from observational studies of telomere length (TL) has been
conflicting regarding its direction of association with cancer risk. We investigated the causal …

Background Telomere shortening has been associated with several lung diseases.
However, telomere length is generally measured in peripheral blood leucocytes rather than …

Background. Fetal heart can regenerate to restore its normal anatomy and function in
response to injury, but this regenerative capacity is lost within the first week of postnatal life …