Epidemiology and risk factors for bipolar disorder

TA Rowland, S Marwaha - Therapeutic advances in …, 2018 - journals.sagepub.com
Bipolar disorder is a multifactorial illness with uncertain aetiology. Knowledge of potential
risk factors enables clinicians to identify patients who are more likely to develop bipolar …

Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions

N Robinson, SE Bergen - Frontiers in genetics, 2021 - frontiersin.org
Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …

Interactions between variation in candidate genes and environmental factors in the etiology of schizophrenia and bipolar disorder: a systematic review

B Misiak, F Stramecki, Ł Gawęda, K Prochwicz… - Molecular …, 2018 - Springer
Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …

Systematic assessment of environmental risk factors for bipolar disorder: an umbrella review of systematic reviews and meta‐analyses

B Bortolato, CA Köhler, E Evangelou… - Bipolar …, 2017 - Wiley Online Library
Objectives The pathophysiology of bipolar disorder is likely to involve both genetic and
environmental risk factors. In our study, we aimed to perform a systematic search of …

Genetic contributions to bipolar disorder: current status and future directions

KS O'Connell, BJ Coombes - Psychological Medicine, 2021 - cambridge.org
Bipolar disorder (BD) is a highly heritable mental disorder and is estimated to affect about 50
million people worldwide. Our understanding of the genetic etiology of BD has greatly …

COVID-19 and first manic episodes: a systematic review

M Russo, D Calisi, MA De Rosa, G Evangelista… - Psychiatry …, 2022 - Elsevier
Sars-CoV-2 is a respiratory virus that can access the central nervous system, as indicated by
the presence of the virus in patients' cerebrospinal fluid and the occurrence of several …

Association between toxoplasmosis and bipolar disorder: A systematic review and meta-analysis

G Cossu, A Preti, D Gyppaz, O Gureje… - Journal of Psychiatric …, 2022 - Elsevier
Background The relationship between toxoplasma gondii (T. gondii) infection and bipolar
disorder (BD) is poorly understood. This review explores this relationship by estimating the …

Toxoplasma gondii, Suicidal Behavior, and Intermediate Phenotypes for Suicidal Behavior

TT Postolache, A Wadhawan, D Rujescu… - Frontiers in …, 2021 - frontiersin.org
Within the general literature on infections and suicidal behavior, studies on Toxoplasma
gondii (T. gondii) occupy a central position. This is related to the parasite's neurotropism …

Is Toxoplasma gondii a Trigger of Bipolar Disorder?

C Del Grande, L Galli, E Schiavi, L Dell'Osso, F Bruschi - Pathogens, 2017 - mdpi.com
Toxoplasma gondii, a ubiquitous intracellular parasite, has a strong tropism for the brain
tissue, where it forms intracellular cysts within the neurons and glial cells, establishing a …

Gene-environment interactions in psychiatry: recent evidence and clinical implications

RJ Musci, JL Augustinavicius, H Volk - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review We identify the recent evidence for gene-by-environment
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …