Sexual dimorphism in innate immunity: the role of sex hormones and epigenetics

R Shepherd, AS Cheung, K Pang, R Saffery… - Frontiers in …, 2021 - frontiersin.org
Sexual dimorphism refers to differences between biological sexes that extend beyond
sexual characteristics. In humans, sexual dimorphism in the immune response has been …

Sex and gender differences in the outcomes of vaccination over the life course

KL Flanagan, AL Fink, M Plebanski… - Annual review of cell …, 2017 - annualreviews.org
Both sex (ie, biological differences) and gender (ie, social or cultural influences) impact
vaccine acceptance, responses, and outcomes. Clinical data illustrate that among children …

Physiologic events of embryo implantation and decidualization in human and non-human primates

MA Ochoa-Bernal, AT Fazleabas - International journal of molecular …, 2020 - mdpi.com
Reproduction is a fundamental process for the preservation of the human species. This
process requires a sequence of orchestrated events that are necessary for a successful …

The endocrine function of human placenta: an overview

MA Costa - Reproductive biomedicine online, 2016 - Elsevier
During pregnancy, several tightly coordinated and regulated processes take place to enable
proper fetal development and gestational success. The formation and development of the …

Endometrial immune dysfunction in recurrent pregnancy loss

C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

Pathogenesis of Zika virus infection

MI Giraldo, M Gonzalez-Orozco… - Annual Review of …, 2023 - annualreviews.org
Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …

Immunology of the maternal-fetal interface

A Erlebacher - Annual review of immunology, 2013 - annualreviews.org
The immune cells that reside at the interface between the placenta and uterus are thought to
play many important roles in pregnancy. Recent work has revealed that the composition and …

Pregnancy and pregnancy-associated hormones alter immune responses and disease pathogenesis

DP Robinson, SL Klein - Hormones and behavior, 2012 - Elsevier
This article is part of a Special Issue “Neuroendocrine-Immune Axis in Health and Disease.”
During pregnancy, it is evolutionarily advantageous for inflammatory immune responses that …

Worse progression of COVID‐19 in men: is testosterone a key factor?

VA Giagulli, E Guastamacchia, T Magrone, E Jirillo… - …, 2021 - Wiley Online Library
Background The novel severe acute respiratory syndrome coronavirus (SARS‐CoV‐2)
disease 2019 (COVID‐19) seems to have a worse clinical course among infected men …

Th1/Th2/Th17 and regulatory T‐cell paradigm in pregnancy

S Saito, A Nakashima, T Shima… - American journal of …, 2010 - Wiley Online Library
Citation Saito S, Nakashima A, Shima T, Ito M. Th1/Th2/Th17 and regulatory T‐cell paradigm
in pregnancy. Am J Reprod Immunol 2010 T‐helper (Th) cells play a central role in …