The effect of silyl substituents in diphenylprolinol silyl ether catalysts was investigated.
Mechanistically, reactions catalyzed by diphenylprolinol silyl ether can be categorized into …

Computational investigation of the aldol reaction of benzaldehyde with acetone catalyzed by
various proline derivatives and 2-azetidine carboxylic acid reveal the origins of …

Irreversibility of thermally denatured proteins due to aggregation limits thermodynamic
characterization of proteins and also confounds the identification of thermostable mutants in …

Asymmetric synthesis of α‐substituted proline derivatives has been accomplished by an
efficient chirality‐transfer method. High diastereoselectivity of the N‐alkylation of the proline …

A molecular dyad, PY-P8-PER, comprising a proline octamer sandwiched between pyrene
and perylene terminals has been synthesized in order to address the dynamics of electronic …

Proline is one of a kind. This amino acid exhibits a variety of unique functions in biological
contexts, which continue to be discovered and developed. In addition to the reactivity of the …

An efficient way to access highly functionalized proline derivatives was developed based on
a Cu (I)-catalyzed reaction between CF3-substituted allenynes and tosylazide, which …

A straightforward synthesis of enantiopure (S)-and (R)-α-Tfm-pyroglutamic acid is reported.
The strategy is based on the use of a chiral CF3-hydroxymorpholinone intermediate …

The cis–trans isomerization and conformer specificity of δ-azaproline and its carbamate-
protected form in linear and cyclic peptides were investigated using NMR and α …

Cα‐Methyl‐l‐proline, or l‐(αMe) Pro, is probably the most conformationally constrained α‐
amino acid. In particular, its ω and ϕ torsion angles are restricted to about 180 and− 60° …