A comprehensive performance evaluation, comparison, and integration of computational methods for detecting and estimating cross-contamination of human samples …

H Chen, B Wang, L Cai, X Yang, Y Hu, Y Zhang… - Journal of Biomedical …, 2024 - Elsevier
Cross-sample contamination is one of the major issues in next-generation sequencing
(NGS)-based molecular assays. This type of contamination, even at very low levels, can …

Detection of insecticide resistance markers in Anopheles funestus from the Democratic Republic of the Congo using a targeted amplicon sequencing panel

H Acford-Palmer, M Campos, J Bandibabone… - Scientific Reports, 2023 - nature.com
Vector control strategies have been successful in reducing the number of malaria cases and
deaths globally, but the spread of insecticide resistance represents a significant threat to …

Rapid profiling of Plasmodium parasites from genome sequences to assist malaria control

JE Phelan, A Turkiewicz, E Manko, J Thorpe… - Genome medicine, 2023 - Springer
Background Malaria continues to be a major threat to global public health. Whole genome
sequencing (WGS) of the underlying Plasmodium parasites has provided insights into the …

Towards environmental detection, quantification, and molecular characterization of Anopheles stephensi and Aedes aegypti from experimental larval breeding sites

M Kristan, H Acford-Palmer, MO Campos, EL Collins… - Scientific Reports, 2023 - nature.com
The invasion and establishment of An. stephensi mosquitoes in the Horn of Africa represents
a significant regional threat, which may jeopardise malaria control, particularly in urban …

Frequencies of insecticide resistance mutations detected by the amplicon sequencing in Plutella xylostella (Lepidoptera: Plutellidae) and Spodoptera exigua …

Z Liu, H Ma, K Li, J Liu, H Zhu, Y Zhou… - Journal of Economic …, 2024 - academic.oup.com
The globally prevalent pests, Diamondback moth, Plutella xylostella (Lepidoptera:
Plutellidae) and Beet armyworm, Spodoptera exigua (Lepidoptera: Noctuidae), pose …

Genomic surveillance of Anopheles mosquitoes on the Bijagós Archipelago using custom targeted amplicon sequencing identifies mutations associated with …

S Moss, E Pretorius, S Ceesay, H Hutchins… - Parasites & …, 2024 - Springer
Background Insecticide resistance is reducing the efficacy of vector control interventions,
consequently threatening efforts to control vector-borne diseases, including malaria …

Application of a targeted amplicon sequencing panel to screen for insecticide resistance mutations in Anopheles darlingi populations from Brazil

H Acford-Palmer, AO Andrade, JE Phelan… - Scientific reports, 2025 - nature.com
Large-scale surveillance and informed vector control approaches are urgently needed to
ensure that national malaria programs remain effective in reducing transmission and …

The cys-loop ligand-gated ion channel gene superfamily of the Colorado potato beetle, Leptinotarsa decemlineata

D Chen, DJ Hawthorne - bioRxiv, 2025 - biorxiv.org
Background: The insect cys-loop ligand-gated ion channel (cysLGIC) superfamily includes
nicotinic acetylcholine receptors (nAChRs), γ-aminobutyric acid (GABA) receptors …

A genomic investigation into three malaria vectors: An. darlingi, An. funestus, and An. stephensi.

H Acford-Palmer - 2024 - researchonline.lshtm.ac.uk
Different Anopheles spp. are able to transmit the Plasmodium parasite, the causative agent
of malaria. Malaria results in over 600,000 deaths a year, predominantly in children and the …

Profiling insecticide resistance phenotypes and genotypes in Aedes aegypti populations across four regions in Puerto Rico

EL Collins, JM Quintana, R Morales… - Available at SSRN …, 2024 - papers.ssrn.com
Vector-borne diseases (VBD) exert a considerable toll on global health, causing significant
morbidity and mortality. Among these, arboviruses like dengue and Zika contribute …