Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

Virus-based nanoparticles as versatile nanomachines

KJ Koudelka, AS Pitek, M Manchester… - Annual review of …, 2015 - annualreviews.org
Nanoscale engineering is revolutionizing the way we prevent, detect, and treat diseases.
Viruses have played a special role in these developments because they can function as …

Plant viruses and bacteriophages for drug delivery in medicine and biotechnology

AE Czapar, NF Steinmetz - Current opinion in chemical biology, 2017 - Elsevier
Highlights•Plant viruses and bacteriophages can be regarded as natural nanoparticles.•Viral
nanoparticles are utilized in nanotechnology targeting diverse applications.•Viral capsids …

Delivery of nematicides using TMGMV-derived spherical nanoparticles

AA Caparco, I González-Gamboa, SS Hays… - Nano Letters, 2023 - ACS Publications
Spherical nanoparticles (SNPs) from tobacco mild green mosaic virus (TMGMV) were
developed and characterized, and their application for agrochemical delivery was …

Plant virus-based materials for biomedical applications: Trends and prospects

S Eiben, C Koch, K Altintoprak, A Southan… - Advanced drug delivery …, 2019 - Elsevier
Nanomaterials composed of plant viral components are finding their way into medical
technology and health care, as they offer singular properties. Precisely shaped, tailored …

The pharmacology of plant virus nanoparticles

CI Nkanga, NF Steinmetz - Virology, 2021 - Elsevier
The application of nanoparticles for medical purposes has made enormous strides in
providing new solutions to health problems. The observation that plant virus-based …

Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer

MA Bruckman, AE Czapar, A VanMeter… - Journal of Controlled …, 2016 - Elsevier
Drug delivery systems are required for drug targeting to avoid adverse effects associated
with chemotherapy treatment regimes. Our approach is focused on the study and …

The protein corona of plant virus nanoparticles influences their dispersion properties, cellular interactions, and in vivo fates

AS Pitek, AM Wen, S Shukla, NF Steinmetz - Small, 2016 - Wiley Online Library
Biomolecules in bodily fluids such as plasma can adsorb to the surface of nanoparticles and
influence their biological properties. This phenomenon, known as the protein corona, is well …

TMV particles: the journey from fundamental studies to bionanotechnology applications

GP Lomonossoff, C Wege - Advances in Virus Research, 2018 - Elsevier
Ever since its initial characterization in the 19th century, tobacco mosaic virus (TMV) has
played a prominent role in the development of modern virology and molecular biology. In …

Modular interior loading and exterior decoration of a virus-like particle

J Sharma, M Uchida, HM Miettinen, T Douglas - Nanoscale, 2017 - pubs.rsc.org
Virus-like particles (VLPs) derived from the bacteriophage P22 offer an interesting and
malleable platform for encapsulation and multivalent presentation of cargo molecules. The …