Despite the recent advances in chemotherapeutic treatments against cancer, some types of
highly aggressive and invasive cancer develop drug resistance against conventional …

Matrix metalloproteinases (MMPs) are an important class of enzymes in the body that
function through the extracellular matrix (ECM). They are involved in diverse …

Colorectal cancer (CRC) develops by genetic and epigenetic alterations. However, the
molecular mechanisms underlying metastatic dissemination remain unclear and could …

Breast cancer stem cells (BCSCs) are unique in their ability to undergo unlimited self-
renewal, an essential process in breast cancer recurrence following metastatic dormancy …

In this study, we explore the dynamic process of colorectal cancer progression, emphasizing
the evolution toward a more metastatic phenotype. The term" evolution" as used in this study …

Background Aberrant DNA methylation patterns of genes required for development are
common in in vitro produced embryos. In this regard, we previously identified altered DNA …

Background DKK1 has been reported to act as a tumor suppressor in breast cancer.
However, the mechanism of DKK1 inhibits breast cancer migration and invasion was still …

DNA methylation is an epigenetic mechanism that plays a key role in regulating gene
expression and other functions. Although this modification is seen in different sequence …

Breast cancer (BRCA) is the most common cancer in the world, of which incidence rate and
mortality are the highest in women. Being responsible for the remodeling and degradation of …

Background: There are no reliable biomarkers to accurately differentiate indolent thyroid
tumors from more aggressive thyroid cancers. This study aimed to develop new DNA …