As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and
mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to …

Human le ishmaniasis is a vector-borne, neglected infectious disease that is widely
distributed in America, Africa, Europe, and Asia. Current therapy is based on old and toxic …

Leishmaniasis is a neglected disease caused by protozoan parasites of the Leishmania
genus, which affects many people in several countries. This disease has three major clinical …

Background Amphotericin B (AmB) as a liposomal formulation of AmBisome is the first line of
treatment for the disease, visceral leishmaniasis, caused by the parasite Leishmania …

Leishmaniasis are a group of neglected infectious diseases caused by protozoa of the
genus Leishmania with distinct presentations. The available leishmaniasis treatment options …

Pentamidine (PTM), which is a diamine that is widely known for its antimicrobial activity, is a
very interesting drug whose mechanism of action is not fully understood. In recent years …

Leishmaniasis is a group of diseases caused by a protozoa parasite from one of over 20
Leishmania species. Depending on the tissues infected, these diseases are classified as …

Parasitic diseases are a neglected and serious problem, especially in underdeveloped
countries. Among the major parasitic diseases, Leishmaniasis figures as an urgent …

Cutaneous leishmaniasis is a worldwide public health problem. Conventional therapies, in
addition to the high cost, have many adverse effects and cases of parasite's resistance …

Abstract Clioquinol (5-chloro-7-iodoquinolin-8-ol or ICHQ) was recently showed to presents
an in vitro effective antileishmanial action, causing changes in membrane permeability …