Challenges and perspectives of DNA nanostructures in biomedicine

A Keller, V Linko - Angewandte Chemie International Edition, 2020 - Wiley Online Library
DNA nanotechnology holds substantial promise for future biomedical engineering and the
development of novel therapies and diagnostic assays. The subnanometer‐level …

DNA nanostructures: current challenges and opportunities for cellular delivery

A Lacroix, HF Sleiman - ACS nano, 2021 - ACS Publications
DNA nanotechnology has produced a wide range of self-assembled structures, offering
unmatched possibilities in terms of structural design. Because of their programmable …

Complex shapes self-assembled from single-stranded DNA tiles

B Wei, M Dai, P Yin - Nature, 2012 - nature.com
Programmed self-assembly of strands of nucleic acid has proved highly effective for creating
a wide range of structures with desired shapes,,,,,,,,,,,,,,,,,,,,,,,,. A particularly successful …

[HTML][HTML] From cascaded catalytic nucleic acids to enzyme–DNA nanostructures: controlling reactivity, sensing, logic operations, and assembly of complex structures

F Wang, CH Lu, I Willner - Chemical reviews, 2014 - ACS Publications
DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …

Sequence-programmable covalent bonding of designed DNA assemblies

T Gerling, M Kube, B Kick, H Dietz - Science advances, 2018 - science.org
Bottom-up fabrication of custom nanostructures using the methods of DNA nanotechnology
has great potential for applications in many areas of science and technology. One obstacle …

Self-assembly of carbon nanotubes into two-dimensional geometries using DNA origami templates

HT Maune, S Han, RD Barish, M Bockrath… - Nature …, 2010 - nature.com
A central challenge in nanotechnology is the parallel fabrication of complex geometries for
nanodevices. Here we report a general method for arranging single-walled carbon …

Virus-encapsulated DNA origami nanostructures for cellular delivery

J Mikkila, AP Eskelinen, EH Niemela, V Linko… - Nano …, 2014 - ACS Publications
DNA origami structures can be programmed into arbitrary shapes with nanometer scale
precision, which opens up numerous attractive opportunities to engineer novel functional …

Self-assembled DNA nanopores that span lipid bilayers

JR Burns, E Stulz, S Howorka - Nano letters, 2013 - ACS Publications
DNA nanotechnology excels at rationally designing bottom-up structures that can
functionally replicate naturally occurring proteins. Here we describe the design and …

Construction of rolling circle amplification products-based pure nucleic acid nanostructures for biomedical applications

C Li, Y Wang, PF Li, Q Fu - Acta Biomaterialia, 2023 - Elsevier
Nucleic acid nanomaterials with good biocompatibility, biodegradability, and
programmability have important applications in biomedical field. Nucleic acid nanomaterials …

Engineering a stable future for DNA-origami as a biomaterial

H Bila, EE Kurisinkal, MMC Bastings - Biomaterials science, 2019 - pubs.rsc.org
DNA as a biomaterial has evoked great interest as a potential platform for therapeutics and
diagnostics and as hydrogel scaffolds due to the relative ease of programming its robust and …