Quinazoline alkaloids and related chemistry

S Eguchi - Bioactive Heterocycles I, 2006 - Springer
Recent progress in quinazoline alkaloids and related chemistry was reviewed focusing on
developments of the synthetic methodologies and their synthetic applications. A brief …

Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents

AR Kotb, DA Bakhotmah, AE Abdallah, H Elkady… - RSC …, 2022 - pubs.rsc.org
Cancer is still a dangerous disease with a high mortality rate all over the world. In our
attempt to develop potential anticancer candidates, new quinazoline and phthalazine based …

Zn (II) complexes of (E)-4-(2-(pyridin-2-ylmethylene) hydrazinyl) quinazoline in combination with non-steroidal anti-inflammatory drug sodium diclofenac: Structure …

C Kakoulidou, PS Gritzapis, AG Hatzidimitriou… - Journal of Inorganic …, 2020 - Elsevier
The interaction of the novel quinazoline (E)-4-(2-(pyridin-2-ylmethylene) hydrazinyl)
quinazoline (L) with Zn 2+ was performed in the absence or presence of the non-steroidal …

Transition metal complexes of 3-aryl-2-substituted 1, 2-dihydroquinazolin-4 (3H)-one derivatives: New class of analgesic and anti-inflammatory agents

RS Hoonur, BR Patil, DS Badiger, RS Vadavi… - European journal of …, 2010 - Elsevier
Five-coordinate, neutral transition metal complexes of newly designed pyridine-2-ethyl-(3-
carboxylideneamino)-3-(2-phenyl)-1, 2-dihydroquinazolin-4 (3H)-one (L) were synthesized …

Novel 3, 3a, 4, 5, 6, 7‐hexahydroindazole and arylthiazolylpyrazoline derivatives as anti‐inflammatory agents

MNA Nasr, SA Said - Archiv der Pharmazie: An International …, 2003 - Wiley Online Library
A novel series of 7‐benzylidene‐3, 3a, 4, 5, 6, 7‐hexahydro‐3‐phenyl‐2H‐indazole
substituted at the 2‐position were synthesized. The reaction of 2, 6‐bis …

A fluorescent chemosensor for the sequential detection of copper (II) and histidine and its biological applications

D Wang, JQ Zheng, XJ Zheng, DC Fang… - Sensors and Actuators B …, 2016 - Elsevier
Abstract A new fluorescent sensor 6-(2, 3-dihydroxyphenyl)-5, 6-dihydrobenzoimidazo [1, 2-
c] quinazoline (H 2 L) and the Zn (II) complex [Zn 2 L 1 2]∙ C 2 H 5 OH (H 2 L 1= 3-{[2-(1H …

New substituted quinazoline analogs: Synthesis, anticancer evaluation and docking study

M Naziri, M Mokhtary, F Safa - Journal of Molecular Structure, 2023 - Elsevier
In this work, fifteen new substituted quinazoline analogs were synthesized in good yields
through the reaction of 7-(2-chloroethoxy)-6-methoxy-N-arylquinazoline-4-amine and …

[PDF][PDF] Studies on some biologically active substituted 4 (3H)-quinazolinones. Part 1. Synthesis, characterization and anti-inflammatory-antimicrobial activity of 6, 8 …

SS Laddha, SG Wadodkar, SK Meghal - Arkivoc, 2006 - arkat-usa.org
Abstract Two series of 6, 8-disubstituted 2-phenyl-3-[substituted benzothiazol-2-yl]-4 (3H)-
quinazolinones [3a-m and 4a-m] have been synthesized and characterized by elemental …

Synthesis and evaluation of some novel quinazolinone derivatives as diuretic agents

AR Maarouf, ER El‐Bendary… - Archiv der Pharmazie: An …, 2004 - Wiley Online Library
A new series of quinazolin‐4 (3H)‐one derivatives containing either a thiazole or a 1, 3, 4‐
thiadiazole moiety were prepared in order to study the effect of such a heterocyclic …

Synthesis, biological evaluation and QSAR study of a series of substituted quinazolines as antimicrobial agents

VM Buha, DN Rana, MT Chhabria… - Medicinal Chemistry …, 2013 - Springer
A novel series of 1-N-substituted-3-(4-(5-(pyridin-3-yl)-1, 3, 4-oxadiazol-2-ylthio) quinazolin-
6-yl) urea/thiourea derivatives (6a–6r) and 1-N-substituted-3-(7-(4-methylpiperazin-1-yl)-4 …