Senescent cells (SCs) arise from normal cells in multiple organs due to inflammatory,
metabolic, DNA damage, or tissue damage signals. SCs are non-proliferating but …

Chronic spontaneous urticaria (CSU) is defined as recurrent episodes of spontaneous
wheal development and/or angioedema for more than six weeks and at least twice a week …

Chronic spontaneous urticaria (CSU) is often associated with organ specific autoimmunity
but is rarely caused by food allergy. Colourings and preservatives in pre-packaged foods, so …

Diabetic nephropathy (DN) is a major complication of diabetes and represents the leading
cause of end-stage renal disease. Mesenchymal stem cell (MSC) treatment has been …

Background Increasing evidence suggests that the gut microbiome plays a role in the
pathogenesis of allergy and autoimmunity. The association between abnormalities in the gut …

The pathogenesis of chronic urticaria is not well delineated and the treatment is palliative as
it is not tied to the pathomechanism. The centrality of mast cells and their inappropriate …

Background Clinical features and basophil activation levels correlate with serum
autoreactivity and allergen sensitivity in patients with chronic spontaneous urticaria (CSU) …

Background Chronic urticaria is defined as repeated episodes of wheals lasting for 6 weeks
or longer. Nowadays, the role of vitamin D in various chronic diseases is a matter of great …

Background Omalizumab, a humanized recombinant monoclonal anti‐IgE antibody, proved
to be effective in patients with chronic spontaneous urticaria (CSU), including severe and …

慢性荨麻疹在临床十分常见， 但目前关于慢性荨麻疹的发病机制尚未完全阐明。
多数患者因找不到确切病因， 造成误诊或治疗不及时。 既往研究发现肥大细胞活化是慢性荨 …