Metabolic acidosis occurs when a relative accumulation of plasma anions in excess of
cations reduces plasma pH. Replacement of sodium bicarbonate to patients with sodium …

Sepsis and septic shock are syndromes of immense clinical importance. Suspected sepsis
accounts for more than half a million emergency department visits annually in the United …

Background Acute acidaemia is frequently observed during critical illness. Sodium
bicarbonate infusion for the treatment of severe metabolic acidaemia is a possible treatment …

Metabolic acidosis is a disorder frequently encountered in emergency medicine and
intensive care medicine. As literature has been enriched with new data concerning the …

Mortality rates associated with severe lactic acidosis (blood pH< 7.2) due to sepsis or low-
flow states are high. Eliminating the triggering conditions remains the most effective therapy …

Background: Pain management is important for ensuring early mobilization after hip
arthroplasty; however, the optimal components remain controversial. Recently, the …

Background Sodium bicarbonate administration during cardiopulmonary resuscitation
(CPR) is controversial. Current guidelines recommend sodium bicarbonate injection in …

Introduction. Sepsis and its consequences such as metabolic acidosis are resulting in
increased mortality. Although correction of metabolic acidosis with sodium bicarbonate …

The management of acid-base disorders always calls for precise diagnosis and treatment of
the underlying disease. Sometimes additional means are necessary to combat systemic …

Lactic acidosis occurs commonly and can be a marker of significant physiologic
derangements. However what an elevated lactate level and acidemia connotes and what …