Cachexia, muscle wasting, and frailty in cardiovascular disease

A Bielecka‐Dabrowa, N Ebner… - European journal of …, 2020 - Wiley Online Library
The last several years have seen increasing interest in understanding cachexia, muscle
wasting, and physical frailty across the broad spectrum of patients with cardiovascular …

Understanding the common mechanisms of heart and skeletal muscle wasting in cancer cachexia

V Rausch, V Sala, F Penna, PE Porporato, A Ghigo - Oncogenesis, 2021 - nature.com
Cachexia is a severe complication of cancer that adversely affects the course of the disease,
with currently no effective treatments. It is characterized by a progressive atrophy of skeletal …

Heart failure in the last year: progress and perspective

D Tomasoni, M Adamo, MS Anker… - ESC heart …, 2020 - Wiley Online Library
Research about heart failure (HF) has made major progress in the last years. We give here
an update on the most recent findings. Landmark trials have established new treatments for …

Frailty and heart failure: State‐of‐the‐art review

KM Talha, A Pandey, M Fudim, J Butler… - Journal of Cachexia …, 2023 - Wiley Online Library
At least half of all patients with heart failure (HF) are affected by frailty, a syndrome that limits
an individual ability to recover from acute stressors. While frailty affects up to 90% of patients …

Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies

GB Kubat, E Bouhamida, O Ulger, I Turkel, G Pedriali… - Mitochondrion, 2023 - Elsevier
Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Defining and diagnosing sarcopenia: is the glass now half full?

R Barazzoni, T Cederholm, M Zanetti, GG Cappellari - Metabolism, 2023 - Elsevier
Low muscle mass and function exert a substantial negative impact on quality of life, health
and ultimately survival, but their definition, identification and combination to define …

Barthel Index Score Predicts Mortality in Elderly Heart Failure―A Goal of Comprehensive Cardiac Rehabilitation―

S Katano, T Yano, K Ohori, H Kouzu, R Nagaoka… - Circulation …, 2021 - jstage.jst.go.jp
Background: A strategy to predict mortality in elderly heart failure (HF) patients has not been
established. Methods and Results: We retrospectively enrolled 413 HF patients aged≥ 65 …

The effect of computed tomography parameters on sarcopenia and myosteatosis assessment: a scoping review

J Lortie, G Gage, B Rush, SB Heymsfield… - Journal of cachexia …, 2022 - Wiley Online Library
Computed tomography (CT) is a valuable assessment method for muscle pathologies such
as sarcopenia, cachexia, and myosteatosis. However, several key underappreciated scan …

A year in heart failure: an update of recent findings

L Stretti, D Zippo, AJS Coats, MS Anker… - ESC Heart …, 2021 - Wiley Online Library
Major changes have occurred in these last years in heart failure (HF) management.
Landmark trials and the 2021 European Society of Cardiology guidelines for the diagnosis …

Sarcopenia and frailty in heart failure: is there a biomarker signature?

R Sato, M Vatic, GWP da Fonseca… - Current heart failure …, 2022 - Springer
Abstract Purpose of Review Sarcopenia and frailty are common in patients with heart failure
(HF) and are strongly associated with prognosis. This review aims to examine promising …