Compelling evidence from basic molecular biology has demonstrated the dual roles of
microglia in the pathogenesis of Alzheimer's disease (AD). On one hand, microglia are …

The six members of the family of insulin-like growth factor (IGF) binding proteins (IGFBPs)
were originally characterized as passive reservoirs of circulating IGFs, but they are now …

Fucosylated carbohydrate structures are involved in a variety of biological and pathological
processes in eukaryotic organisms including tissue development, angiogenesis, fertilization …

Glycosylation is one of the most common post‐translational modification reactions and
nearly half of all known proteins in eukaryotes are glycosylated. In fact, changes in …

Insulin-like growth factor binding protein-3 (IGFBP-3) is a p53 tumor suppressor-regulated
protein and a major carrier for IGFs in circulation. Among six high-affinity IGFBPs, which are …

Among the various posttranslational modification reactions, glycosylation is the most
common, and nearly 50% of all known proteins are thought to be glycosylated. In particular …

Glycosylation is one of the most common post‐translational modifications, and
approximately 50% of all proteins are presumed to be glycosylated in eukaryotes. Branched …

Glycosylation is a posttranslational modification of proteins playing a major role in cell
signalling, immune recognition, and cell‐cell interaction because of their glycan branches …

Aims Non-compaction cardiomyopathy is a devastating genetic disease caused by
insufficient consolidation of ventricular wall muscle that can result in inadequate cardiac …

Background Body traits are generally controlled by several genes in vertebrates (ie
polygenes), which in turn make them difficult to identify through association mapping …