Colorectal cancer (CRC), a leading cause of cancer-related mortalities globally, results from
the accumulation of multiple genetic and epigenetic alterations in the normal colonic and …

Cancer is a complex deadly disease that has caused a global health crisis in recent epochs.
Colorectal cancer (CRC) is the third most common malignant gastrointestinal disease. It has …

Background Accumulating evidence suggests that circular RNAs (circRNAs) are important
participants in cancer progression. However, the biological processes and underlying …

The tumor microenvironment (TME) is populated by abundant cancer-associated fibroblasts
(CAFs) that radically influence the disease progression across many cancers, including the …

Background cAMP responsive element binding protein 5 (CREB5) is a transcriptional
activator in eukaryotic cells that can regulate gene expression. Previously, we found that …

Background Colorectal cancer (CRC) with a high prevalence is recognized as the fourth
most common cause of cancer‐related death globally. Over the past decade, there has been …

Colorectal cancer (CRC) is one of the deadliest cancers in the world, the incidences and
morality rate are rising and poses an important threat to the public health. It is known that …

The MET proto-oncogene was first identified in osteosarcoma cells exposed to carcinogens.
Although expressed in many normal cells, MET is overexpressed in many human cancers …

Simple Summary The MET gene is crucial for cell growth and has shown promise as a
cancer treatment target. However, distinguishing between focal amplification and polysomy …

Platelets have been recognized as key players in hemostasis, thrombosis, and cancer.
Preclinical and clinical researches evidenced that tumorigenesis and metastasis can be …