A review of micronutrients and the immune system–working in harmony to reduce the risk of infection

AF Gombart, A Pierre, S Maggini - Nutrients, 2020 - mdpi.com
Immune support by micronutrients is historically based on vitamin C deficiency and
supplementation in scurvy in early times. It has since been established that the complex …

Immune function and micronutrient requirements change over the life course

S Maggini, A Pierre, PC Calder - Nutrients, 2018 - mdpi.com
As humans age, the risk and severity of infections vary in line with immune competence
according to how the immune system develops, matures, and declines. Several factors …

Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells

D Chauss, T Freiwald, R McGregor, B Yan, L Wang… - Nature …, 2022 - nature.com
The molecular mechanisms governing orderly shutdown and retraction of CD4+ type 1
helper T (TH1) cell responses remain poorly understood. Here we show that complement …

[HTML][HTML] Antimicrobial peptides: an emerging category of therapeutic agents

M Mahlapuu, J Håkansson, L Ringstad… - Frontiers in cellular and …, 2016 - frontiersin.org
Antimicrobial peptides (AMPs), also known as host defense peptides, are short and
generally positively charged peptides found in a wide variety of life forms from …

[HTML][HTML] Antibiotic resistance in agriculture: Perspectives on upcoming strategies to overcome upsurge in resistance

A Mann, K Nehra, JS Rana, T Dahiya - Current research in microbial …, 2021 - Elsevier
Antibiotic resistance is a massive problem rising constantly and spreading rapidly since the
past decade. The major underlying mechanism responsible for this problem is an overuse or …

[HTML][HTML] Modest effects of dietary supplements during the COVID-19 pandemic: insights from 445 850 users of the COVID-19 Symptom Study app

P Louca, B Murray, K Klaser, MS Graham… - … nutrition, prevention & …, 2021 - ncbi.nlm.nih.gov
Objectives Dietary supplements may ameliorate SARS-CoV-2 infection, although scientific
evidence to support such a role is lacking. We investigated whether users of the COVID-19 …

Quercetin in the prevention and treatment of coronavirus infections: a focus on SARS-CoV-2

A Gasmi, PK Mujawdiya, R Lysiuk, M Shanaida… - Pharmaceuticals, 2022 - mdpi.com
The COVID-19 outbreak seems to be the most dangerous challenge of the third millennium
due to its highly contagious nature. Amongst natural molecules for COVID-19 treatment, the …

Nutrition and immune system: from the Mediterranean diet to dietary supplementary through the microbiota

L Barrea, G Muscogiuri, E Frias-Toral… - Critical reviews in …, 2021 - Taylor & Francis
The interaction between nutrition and the immune system is very complex. In particular, at
every stage of the immune response, specific micronutrients, including vitamins and …

Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data

L Rejnmark, LS Bislev, KD Cashman, G Eiríksdottir… - PloS one, 2017 - journals.plos.org
Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

Vitamin D—effects on skeletal and extraskeletal health and the need for supplementation

M Wacker, MF Holick - Nutrients, 2013 - mdpi.com
Vitamin D, the sunshine vitamin, has received a lot of attention recently as a result of a
meteoric rise in the number of publications showing that vitamin D plays a crucial role in a …