Genomic innovation and regulatory rewiring during evolution of the cotton genus Gossypium

M Wang, J Li, Z Qi, Y Long, L Pei, X Huang… - Nature Genetics, 2022 - nature.com
Phenotypic diversity and evolutionary innovation ultimately trace to variation in genomic
sequence and rewiring of regulatory networks. Here, we constructed a pan-genome of the …

Regulatory controls of duplicated gene expression during fiber development in allotetraploid cotton

J You, Z Liu, Z Qi, Y Ma, M Sun, L Su, H Niu, Y Peng… - Nature …, 2023 - nature.com
Polyploidy complicates transcriptional regulation and increases phenotypic diversity in
organisms. The dynamics of genetic regulation of gene expression between coresident …

[HTML][HTML] HIV-1 integration landscape during latent and active infection

LB Cohn, IT Silva, TY Oliveira, RA Rosales, EH Parrish… - Cell, 2015 - cell.com
The barrier to curing HIV-1 is thought to reside primarily in CD4+ T cells containing silent
proviruses. To characterize these latently infected cells, we studied the integration profile of …

Genome of Solanum pimpinellifolium provides insights into structural variants during tomato breeding

X Wang, L Gao, C Jiao, S Stravoravdis… - Nature …, 2020 - nature.com
Solanum pimpinellifolium (SP) is the wild progenitor of cultivated tomato. Because of its
remarkable stress tolerance and intense flavor, SP has been used as an important …

RNA sequencing provides insights into the evolution of lettuce and the regulation of flavonoid biosynthesis

L Zhang, W Su, R Tao, W Zhang, J Chen, P Wu… - Nature …, 2017 - nature.com
Different horticultural types of lettuce exhibit tremendous morphological variation. However,
the molecular basis for domestication and divergence among the different horticultural types …

Combined GWAS and eQTL analysis uncovers a genetic regulatory network orchestrating the initiation of secondary cell wall development in cotton

Z Li, P Wang, C You, J Yu, X Zhang, F Yan… - New …, 2020 - Wiley Online Library
The cotton fibre serves as a valuable experimental system to study cell wall synthesis in
plants, but our understanding of the genetic regulation of this process during fibre …

Distant eQTLs and non-coding sequences play critical roles in regulating gene expression and quantitative trait variation in maize

H Liu, X Luo, L Niu, Y Xiao, L Chen, J Liu, X Wang… - Molecular Plant, 2017 - cell.com
A detailed understanding of genetic architecture of mRNA expression by millions of genetic
variants is important for studying quantitative trait variation. In this study, we identified 1.25 M …

Obesity increases genomic instability at DNA repeat-mediated endogenous mutation hotspots

P Kompella, G Wang, RE Durrett, Y Lai, C Marin… - Nature …, 2024 - nature.com
Obesity is associated with increased cancer risk, yet the underlying mechanisms remain
elusive. Obesity-associated cancers involve disruptions in metabolic and cellular pathways …

eQTLs play critical roles in regulating gene expression and identifying key regulators in rice

C Liu, X Zhu, J Zhang, M Shen, K Chen… - Plant biotechnology …, 2022 - Wiley Online Library
The regulation of gene expression plays an essential role in both the phenotype and
adaptation of plants. Transcriptome sequencing enables simultaneous identification of …

A combination of genome‐wide and transcriptome‐wide association studies reveals genetic elements leading to male sterility during high temperature stress in cotton

Y Ma, L Min, J Wang, Y Li, Y Wu, Q Hu, Y Ding… - New …, 2021 - Wiley Online Library
Global warming has reduced the productivity of many field‐grown crops, as the effects of
high temperatures can lead to male sterility in such plants. Genetic regulation of the high …