Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is
considered an inflammatory demyelinating and neurodegenerative disorder of the central …

Multiple sclerosis (MS) has been associated with HLA‐DR2 for more than 20 years, and a
large number of studies have addressed the relation between MS and the HLA class II …

Acknowledgments: This study was supported by grants from the Swedish Medical Research
Council, the Childrens' Cancer Foundation, the Tobias Foundation and the Swedish …

Objective: To verify incidence rates and their temporal trend in a homogeneous, ethnically,
and genetically distinct population of central Sardinia (the Nuoro province). Background …

Epidemiological studies have implicated an interplay between genetic and environmental
factors in the aetiology of multiple sclerosis (MS). There is a familial recurrence rate of …

Objective To look for HLA class II alleles and haplotypes conferring susceptibility to multiple
sclerosis (MS) in the Jewish population of Israel. Design Population-based cohort of …

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system and a
leading cause of neurological disability in young adults. Clinical presentation and disease …

Multiple sclerosis (MS) is an autoimmune disease of the CNS in which the interaction
between genetic and environmental factors plays an important role in disease pathogenesis …

Multiple sclerosis (MS), an inflammatory and demyelinating autoimmune disease of CNS
has both, a genetic and an environmental predisposition. Among all the genetic factors …

We analyzed the HLA class II haplotypes in 249 Finnish nuclear families and compared the
frequencies of parental haplotypes transmitted or non-transmitted to multiple sclerosis (MS) …