An international panel of multidisciplinary experts convened to develop recommendations
for managing patients with colorectal cancer (CRC) and synchronous liver metastases …

Colorectal cancer (CRC) is one of the most common cancers in the world. About two third of
patients with CRC will develop distant recurrence at some point in time. Liver is the most …

Colorectal cancer is a prevalent disease worldwide, with more than 50% of patients
developing metastases to the liver. Despite advances in improving resectability, most …

Objective: To apply the principles of the Metro-ticket paradigm to develop a prognostic
model for patients undergoing hepatic resection of colorectal liver metastasis (CRLM) …

Background Colorectal cancer (CRC) is a leading cause of cancer-associated deaths with
liver metastases developing in 25–30% of those affected. Previous data suggest a survival …

Systemic therapy often results in the reduction of tumor size but rarely succeeds in
eradicating all cancer cells. Drug efflux, persistence of cancer stem cells (CSCs), epithelial …

Importance BRAFmutations are reportedly associated with aggressive tumor biology.
However, in contrast with primary colorectal cancer, the association of V600E and non …

Objective: To determine the impact of RAS mutation status on the traditional clinical score (t-
CS) to predict survival after resection of colorectal liver metastases (CLM). Background: The …

Background Hepatic resection is considered the optimal potentially curative treatment for
colorectal liver metastases (CRLM). Following resection, up to two-thirds of patients will …

Purpose: Somatic gene mutations have been increasingly recognized to impact prognosis
following resection of colorectal liver metastases (CLM). We aimed to determine the impact …