Syphilis laboratory guidelines: performance characteristics of nontreponemal antibody tests

S Tuddenham, SS Katz… - Clinical Infectious …, 2020 - academic.oup.com
We reviewed the relevant syphilis diagnostic literature to address the following question:
what are the performance characteristics, stratified by the stage of syphilis, for …

[HTML][HTML] CDC laboratory recommendations for syphilis testing, United States, 2024

JR Papp - MMWR. Recommendations and Reports, 2024 - cdc.gov
This report provides new CDC recommendations for tests that can support a diagnosis of
syphilis, including serologic testing and methods for the identification of the causative agent …

Development of a colloidal gold-immunochromatography assay to detect immunoglobulin G antibodies to Treponema pallidum with TPN17 and TPN47

LR Lin, ZG Fu, B Dan, GJ Jing, M Tong, DT Chen… - … and infectious disease, 2010 - Elsevier
Syphilis remains a worldwide public health problem; it is necessary to develop a new
diagnostic approach that is easier and faster than conventional tests. Here, we report a new …

A novel pan-proteome array for high-throughput profiling of the humoral response to Treponema pallidum

JJ Campo, E Romeis, A Oberai, JV Pablo, C Hung… - iScience, 2024 - cell.com
Given the resurgence of syphilis, research endeavors to improve current assays for
serological diagnosis and management of this disease are a priority. A proteome-scale …

Evaluation of immunoglobulin M and G Western blot and ELISA for screening antibodies to Treponema pallidum in blood donors

LN Wang, JM Li - Sexually transmitted diseases, 2009 - journals.lww.com
Evaluation of Immunoglobulin M and G Western Blot and ELISA... : Sexually Transmitted
Diseases Evaluation of Immunoglobulin M and G Western Blot and ELISA for Screening …

Treponema pallidum-specific immune responses and autoimmunity in patients who remain serofast after treatment of syphilis

M Pastuszczak, A Kotnis-Gąska… - … in Dermatology and …, 2019 - termedia.pl
Aim To better understand and investigate the serofast condition, we analyzed an antigen-
specific immune response that occurs during the infection and after the therapy. Since non …

[HTML][HTML] Performance evaluation of eight treponemal antibody tests in China

D Xia, L Yuan, Q Zhou, S Chen, X Chen… - … Microbiology and Infectious …, 2022 - Elsevier
In this study, the performance of 8 commercially available treponemal antibody tests was
evaluated. Higher specificity was achieved in the automated chemiluminescence …

Evaluation of the Determine Syphilis TP assay for the detection of antibodies against Treponema pallidum for the serodiagnosis of syphilis

YH Zhuang, Y Tian, Y Chen, J Tang, JQ Wang… - European journal of …, 2012 - Springer
Currently, infectious syphilis has been resurgent in China and has become a significant
public health problem. The rapid expansion of syphilis screening programs is urgently …

Serological Diagnosis of Syphilis: Enzyme‐Linked Immunosorbent Assay to Measure Antibodies to Individual Recombinant Treponema pallidum Antigens

IE Martin, A Lau, P Sawatzky, RSW Tsang… - … of Immunoassay and …, 2008 - Taylor & Francis
We standardized an indirect ELISA for measurement of serum antibody levels to four
individual treponemal recombinant proteins that have been commonly used in a number of …

Profile of anti-Tp47 antibodies in patients with positive serology for syphilis analized by Western Blot

APF Miranda, NS Sato - Brazilian Journal of Infectious Diseases, 2008 - SciELO Brasil
In Brazil, syphilis is still a great problem of public health. Serological test is essential for
syphilis diagnosis and the current trend is the use of recombinant antigen in the treponemal …