The CD8 T cell-Epstein-Barr virus-B cell trialogue: a central issue in multiple sclerosis pathogenesis
C Veroni, F Aloisi - Frontiers in immunology, 2021 - frontiersin.org
The cause and the pathogenic mechanisms leading to multiple sclerosis (MS), a chronic
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …
Smouldering lesion in MS: Microglia, lymphocytes and pathobiochemical mechanisms
Multiple sclerosis (MS) is an immune-mediated, chronic inflammatory, demyelinating, and
neurodegenerative disease of the central nervous system (CNS). Immune cell infiltration can …
neurodegenerative disease of the central nervous system (CNS). Immune cell infiltration can …
Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis
Epstein-Barr virus (EBV) infection has been advocated as a prerequisite for developing
multiple sclerosis (MS) and possibly the propagation of the disease. However, the precise …
multiple sclerosis (MS) and possibly the propagation of the disease. However, the precise …
Human herpesvirus 6A and axonal injury before the clinical onset of multiple sclerosis
Recent research indicates that multiple sclerosis is preceded by a prodromal phase with
elevated levels of serum neurofilament light chain (sNfL), a marker of axonal injury. The …
elevated levels of serum neurofilament light chain (sNfL), a marker of axonal injury. The …
Cytomegalovirus seropositivity is associated with reduced risk of multiple sclerosis—A presymptomatic case–control study
Abstract Background and purpose Epstein–Barr virus (EBV) and human herpesvirus 6A
(HHV‐6A) are associated with increased risk of multiple sclerosis (MS). Conversely …
(HHV‐6A) are associated with increased risk of multiple sclerosis (MS). Conversely …
Role of environmental factors in multiple sclerosis
Introduction Environmental factors play a significant role in the pathogenesis and
progression of multiple sclerosis (MS), either acting alone or by interacting with other …
progression of multiple sclerosis (MS), either acting alone or by interacting with other …
Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism
OG Thomas, A Rickinson… - Clinical & Translational …, 2023 - Wiley Online Library
Abstract The link between Epstein–Barr virus (EBV) and multiple sclerosis (MS) has puzzled
researchers since it was first discovered over 40 years ago. Until that point, EBV was …
researchers since it was first discovered over 40 years ago. Until that point, EBV was …
Epstein-Barr virus, interleukin-10 and multiple sclerosis: A ménage à trois
G Schönrich, MO Abdelaziz, MJ Raftery - Frontiers in Immunology, 2022 - frontiersin.org
Multiple Sclerosis (MS) is an autoimmune disease that is characterized by inflammation and
demyelination of nerve cells. There is strong evidence that Epstein-Barr virus (EBV), a …
demyelination of nerve cells. There is strong evidence that Epstein-Barr virus (EBV), a …
[HTML][HTML] Epstein–Barr viruses: their immune evasion strategies and implications for autoimmune diseases
Y Zhao, Q Zhang, B Zhang, Y Dai, Y Gao, C Li… - International journal of …, 2024 - mdpi.com
Epstein–Barr virus (EBV), a member of the γ-herpesvirus family, is one of the most prevalent
and persistent human viruses, infecting up to 90% of the adult population globally. EBV's life …
and persistent human viruses, infecting up to 90% of the adult population globally. EBV's life …
Identification of host–pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank
Certain infectious agents are recognised causes of cancer and other chronic diseases. To
understand the pathological mechanisms underlying such relationships, here we design a …
understand the pathological mechanisms underlying such relationships, here we design a …