Addressing the perfect storm: biomarkers in obesity and pathophysiology of cardiometabolic risk

K Aleksandrova, D Mozaffarian, T Pischon - Clinical chemistry, 2018 - academic.oup.com
BACKGROUND The worldwide rise of obesity has provoked intensified research to better
understand its pathophysiology as a means for disease prevention. Several biomarkers that …

The Gut Microbial Regulation of Epigenetic Modification from a Metabolic Perspective

X Lin, H Han, N Wang, C Wang, M Qi, J Wang… - International Journal of …, 2024 - mdpi.com
Obesity is a global health challenge that has received increasing attention in contemporary
research. The gut microbiota has been implicated in the development of obesity, primarily …

Differential regulatory roles of MicroRNAs in porcine intramuscular and subcutaneous adipocytes

K Xu, M Ji, X Huang, Y Peng, W Wu… - Journal of agricultural …, 2020 - ACS Publications
The deposition of intramuscular (IM) and subcutaneous (SC) fat is an important trait
influencing pork quality. Understanding the genetic differences between these two types of …

MiR-375 silencing attenuates pro-inflammatory macrophage response and foam cell formation by targeting KLF4

Y Qiu, J Xu, L Yang, G Zhao, J Ding, Q Chen… - Experimental Cell …, 2021 - Elsevier
Macrophage mediated inflammation and foam cell formation play crucial roles in the
development of atherosclerosis. MiR-375 is a small noncoding RNA that significantly …

MicroRNA-22 inhibition promotes the development of atherosclerosis via targeting interferon regulator factor 5

Z Wu, J Geng, Y Bai, Y Qi, C Chang, Y Jiao… - Experimental Cell …, 2021 - Elsevier
Atherosclerosis is generally accepted as a chronic inflammatory disease and is the most
important pathological process underlying the cardiovascular diseases. MiR-22 exerts an …

Circulating microRNAs associated with C-type natriuretic peptide in childhood obesity

M Cabiati, E Randazzo, C Salvadori, D Peroni… - Peptides, 2020 - Elsevier
Circulating microRNAs (miRNAs) are potential biomarkers of metabolic disease implicated
in the pathogenesis of obesity and at present, no data are available on a possible …

Attenuated macrophage activation mediated by microRNA‑183 knockdown through targeting NR4A2

FH Gong, L Long, YS Yang… - Experimental and …, 2021 - spandidos-publications.com
Atherosclerosis is considered a chronic inflammatory disease, and macrophages function as
important mediators in the development of atherogenesis. MicroRNA (miR)‑183 is a small …

Mirna expression assays

C Braicu, D Gulei, B de Melo Maia… - Genomic Applications in …, 2019 - Springer
MicroRNAs (miRNAs) are small noncoding RNAs able to modulate at transcriptional level
the expression of their target genes. Deregulations in miRNA expression profiles have been …