The sheep as a large animal model for the investigation and treatment of human disorders

A Banstola, JNJ Reynolds - Biology, 2022 - mdpi.com
Simple Summary We review the value of large animal models for improving the translation of
biomedical research for human application, focusing primarily on sheep. Abstract An …

Investigation of potency and safety of live-attenuated peste des petits ruminant virus vaccine in goats by detection of cellular and humoral immune response

M Milovanović, K Dietze, U Wernery, B Hoffmann - Viruses, 2023 - mdpi.com
The peste des petits ruminant (PPR) virus is a transboundary virus found in small domestic
ruminants that causes high morbidity and mortality in naive herds. PPR can be effectively …

A morbillivirus infection shifts DC maturation toward a tolerogenic phenotype to suppress T cell activation

D Rodríguez-Martín, I García-García, V Martín… - Journal of …, 2022 - Am Soc Microbiol
Viruses have evolved numerous strategies to impair immunity so that they can replicate
more efficiently. Among those, the immunosuppressive effects of morbillivirus infection can …

[HTML][HTML] Changes in m6A RNA methylation of goat lung following PPRV infection

RIN Khan, MR Praharaj, WA Malla, N Hosamani… - Heliyon, 2023 - cell.com
Peste des petits ruminants (PPR) is an acute, highly contagious viral disease of goats and
sheep, caused by the Peste des petits ruminants virus (PPRV). Earlier studies suggest the …

Proteome Modulation in Peripheral Blood Mononuclear Cells of Peste des Petits Ruminants Vaccinated Goats and Sheep

SA Wani, AR Sahu, RIN Khan, MR Praharaj… - Frontiers in Veterinary …, 2021 - frontiersin.org
In the present study, healthy goats and sheep (n= 5) that were confirmed negative for peste
des petits ruminants virus (PPRV) antibodies by monoclonal antibody-based competitive …