Neonatal abstinence syndrome

P Kocherlakota - Pediatrics, 2014 - publications.aap.org
Neonatal abstinence syndrome (NAS) is a result of the sudden discontinuation of fetal
exposure to substances that were used or abused by the mother during pregnancy …

[HTML][HTML] The neurobiology of opioid dependence: implications for treatment

TR Kosten, TP George - Science & practice perspectives, 2002 - ncbi.nlm.nih.gov
Opioid tolerance, dependence, and addiction are all manifestations of brain changes
resulting from chronic opioid abuse. The opioid abuser's struggle for recovery is in great part …

Development of a cascade of care for responding to the opioid epidemic

AR Williams, EV Nunes, A Bisaga… - The American journal …, 2019 - Taylor & Francis
Amid worsening opioid overdose death rates, the nation continues to face a persistent
addiction treatment gap limiting access to quality care for opioid use disorder (OUD). Three …

Barriers to primary care physicians prescribing buprenorphine

E Hutchinson, M Catlin, CHA Andrilla… - The Annals of Family …, 2014 - Annals Family Med
PURPOSE Despite the efficacy of buprenorphine-naloxone for the treatment of opioid use
disorders, few physicians in Washington State use this clinical tool. To address the acute …

Methadone‐related opioid agonist pharmacotherapy for heroin addiction: history, recent molecular and neurochemical research and future in mainstream medicine

MJ Kreek - Annals of the New York Academy of Sciences, 2000 - Wiley Online Library
In 1963, Professor Vincent P. Dole at the Rockefeller University formed a small team to
develop a pharmacotherapy for the management of heroin addiction. They hypothesized …

Article Commentary: Underutilization of Medications to Treat Opioid Use Disorder: What Role Does Stigma Play?

B Allen, ML Nolan, D Paone - Substance abuse, 2019 - journals.sagepub.com
There is consensus in the scientific literature that the opioid agonist medications methadone
and buprenorphine are the most effective treatments for opioid use disorder. Despite …

Buprenorphine-naloxone therapy in pain management

KY Chen, L Chen, J Mao - Survey of Anesthesiology, 2014 - journals.lww.com
Chronic pain can be devastating and has enormous impact on quality of life, health care
costs, and work productivity. Although many opioid medications have been developed, with …

Methadone maintenance treatment programme reduces criminal activity and improves social well-being of drug users in China: a systematic review and meta-analysis

HM Sun, XY Li, EPF Chow, T Li, Y Xian, YH Lu… - BMJ open, 2015 - bmjopen.bmj.com
Objective Methadone maintenance treatment (MMT) has been implemented in China since
2004 and has expanded into a nationwide programme. This study aims to evaluate changes …

Two steps forward, one step back: current harm reduction policy and politics in the United States

E Nadelmann, L LaSalle - Harm Reduction Journal, 2017 - Springer
Harm reduction policies and attitudes in the United States have advanced substantially in
recent years but still lag behind more advanced jurisdictions in Europe and elsewhere. The …

Pharmacologic treatment of heroin-dependent patients

PG O'Connor, DA Fiellin - Treatment of Substance Use Disorders, 2013 - taylorfrancis.com
Illicit drug use is responsible for more than 25,000 deaths and $100 billion in total economic
costs annually in the United States (Harwood, Fountain, & Livermore, 1998). Recently …