Despite tremendous successes in the field of antibiotic discovery seen in the previous
century, infectious diseases have remained a leading cause of death. More specifically …

Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

The coarse-grained Martini force field is widely used in biomolecular simulations. Here we
present the refined model, Martini 3 (http://cgmartini. nl), with an improved interaction …

Gram-negative bacteria and their complex cell envelope, which comprises an outer
membrane and an inner membrane, are an important and attractive system for studying the …

Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

The outer membrane of Gram-negative bacteria is unique in both structure and function. The
surface-exposed outer leaflet is composed of lipopolysaccharide, while the inner leaflet is …

β Barrel outer membrane proteins (OMPs) cluster into supramolecular assemblies that give
function to the outer membrane (OM) of Gram-negative bacteria. How such assemblies form …

The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …

Some bacterial species are deadly disease-causing pathogens with high morbidity and
mortality in humans worldwide. Key interfaces in the transmission of bacterial pathogens …

β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …