The hippocampus is a crucial brain region involved in the process of forming and
consolidating memories. Memories are consolidated in the brain through synaptic plasticity …

Designer receptors exclusively activated by designer drug (DREADDs) are a novel tool with
the potential to bidirectionally drive cellular, circuit, and ultimately, behavioral changes. We …

A reduction in taurine content accompanies the ageing process in many tissues. In fact, the
decline of brain taurine levels has been associated with cognitive deficits whereas chronic …

Aging-related biochemical changes in nerve cells lead to dysfunctional synapses and
disrupted neuronal circuits, ultimately affecting vital processes such as brain plasticity …

The dopamine transporter (DAT) is the main target of methylphenidate (MPH), which
remains the number one drug prescribed worldwide for the treatment of Attention-Deficit …

Traumatic brain injury (TBI) is a leading cause of death and long-term disability worldwide.
Although chronic disability is common after TBI, effective treatments remain elusive and …

Schizophrenia is a disorder with a higher cognitive decline in early adulthood, causing
impaired retention of episodic memories. However, the physiological and behavioral …

The psychostimulant methylphenidate (MPH) is increasingly used in the treatment of
attention deficit hyperactivity disorder (ADHD). While there is little evidence for common …

Abnormal plasticity has been reported in the brain of patients with Parkinson's disease (PD),
especially in the striatum. Although both l-Dopa and dopamine agonist remain to be the …

Classical cystathionine β‐synthase‐deficient homocystinuria (HCU) is a life‐threatening
inborn error of sulfur metabolism. Treatment for pyridoxine‐nonresponsive HCU involves …