Mass spectrometry is a central technology in the life sciences, providing our most
comprehensive account of the molecular inventory of the cell. In parallel with developments …

Capillary electrophoresis (CE) has emerged as a powerful technique for comprehensive
physicochemical characterization of monoclonal antibodies (mAbs) as well as other …

The rapid growth of biotherapeutic industry, with more and more complex molecules
entering the market, forces the need for advanced analytical platforms that can quickly and …

The multi-attribute method (MAM) is a liquid chromatography-mass spectrometry (LC-MS)-
based method that is used to directly characterize and monitor numerous product quality …

Charge sensitive separation methods such as ion exchange chromatography (CEX) and
capillary electrophoresis (CE) have recently been coupled to mass spectrometry to facilitate …

The role of mass spectrometry (MS) has become more important in most application
domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation …

The multi-attribute method (MAM), a liquid chromatography-mass spectrometry (LC-MS)-
based peptide mapping method, has gained increased interest and applications in the …

Real-time monitoring of biopharmaceutical reactors is becoming increasingly important as
the processes become more complex. During the continuous manufacturing of monoclonal …

The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize
best practices, share experiences, and generate innovative methodologies to facilitate …

Significant growth of biopharmaceuticals requires powerful analytical methods to better
understand their structure by establishing a complete characterization. To this end, a …