DNA protection, molecular docking, enzyme inhibition and enzyme kinetic studies of 1,5,9-epideoxyloganic acid isolated from Nepeta aristata with bio-guided …

Y Başar, S Yenigün, Y İpek, L Behçet… - Journal of …, 2023 - Taylor & Francis
epideoxyloganic acid (ELA) was isolated from the aerial parts of endemic Nepeta aristata
Boiss Et Kotschy Ex Boiss crude extract (methanol: chloroform) using silica gel (hexane …

In vitro bioactivities and in silico enzyme interactions of abietatrien-3β-ol by bio-guided isolation from Nepeta italica subsp. italica

Y İpek, Y Başar, S Yenigün, L Behçet… - Journal of …, 2024 - Taylor & Francis
Abstract Abietatrien-3 β-ol (ATO) was isolated from the aerial part of the Nepeta italica
subsp. italica methanol-chloroform extract and studied antioxidant, enzyme inhibition, and …

Phytochemical profiling, molecular docking and ADMET prediction of crude extract of Atriplex nitens Schkuhr for the screening of antioxidant and urease inhibitory

Y Başar, S Yenigün, F Gül, T Ozen… - … Journal of Chemistry …, 2024 - dergipark.org.tr
Atriplex nitens Schkuhr (ANS), which grows naturally in arid and semi-arid regions of the
world, is highly resistant to drought and salty environments and is used as food and animal …

Isolation, characterization and evaluation of oxypeucedanin and osthol from local endemic Prangos aricakensis Behçet and Yapar root as antioxidant, enzyme …

SŞ Gökçimen, Y İpek, L Behçet… - Journal of …, 2024 - Taylor & Francis
Prangos species were previously used against many disorders due to their chemical
component. Prangos aricakensis Behçet & Yapar is a newly discovered local endemic …

A potential DNA protector, enzyme inhibitor and in silico studies of daucosterol isolated from six Nepeta species

S Yenigun, Y Basar, Y Ipek, M Gok, L Behcet… - Process …, 2024 - Elsevier
Daucosterol (DAU) was isolated from the methanol-chloroform crude extract of six Nepeta
species (N. aristata, N. baytopii, N. italica, N. nuda albiflora, N. stenantha and N …

Characterization and Comparative Investigation of In Vitro Bioactivities for Lactuca anatolica Root Aqueous Extract and Their Green-Chemical Synthesized …

N Nayel, S Marah, T Ozen, I Yıldız, R Erenler, L Behcet - BioNanoScience, 2024 - Springer
The current study synthesized silver nanoparticle (AgNP) biosynthesis and sustainable
biochemical approaches, molecular docking studies using endemic and medicinal L …

Comprehensive evaluation of Ixoroside: An iridoid glycoside from Nepeta aristata and N. baytopii, assessing antioxidant, antimicrobial, enzyme inhibitory, DNA …

S Yenigun, Y Basar, Y Ipek, L Behcet… - Journal of Biologically …, 2024 - Taylor & Francis
Ixoroside, an iridoid glycoside, was isolated from two endemic plants, Nepeta aristata and
Nepeta baytopii and its structure was elucidated by comprehensive analysis with NMR and …

In Vitro Bioactivities and In Silico ADME Profile for Potential Biological Target Prediction of Selected Phytochemicals Using Six Nepeta Species

S Yenigun, Y Basar, F Gül, Y Ipek, M Gok… - …, 2024 - Wiley Online Library
Several Nepeta species, used in traditional uses, represent sources of valuable
phytochemical composition, as well as in vitro biological and in silico clinical activities. In the …

Chemical Constituents and Bioactivities of Nepeta Taxa Essential Oils from Turkey: Principal Component Analysis, Molecular Docking Study, Molecular Dynamics …

S Yenigun, Y Basar, F Gul, S Marah, L Behcet… - …, 2024 - Wiley Online Library
Nepeta taxa are popular plants and sources of traditional Turkish medicine. Chemical
constituents in the essential oils (EOs) hydrodistilled from above‐ground parts of Nepeta …

The Investigation of the Synthesis, Characterization, Molecular Docking, and Pharmacokinetic Properties of New Thiocarbohydrazones Based on Schiff Bases

NT Karakullukcu - 2024 - preprints.org
Ten new Schiff bases, including thiocarbohydrazone derivatives (1–10), were synthesized
using an efficient, uncomplicated, and environmentally friendly approach using the reaction …