Machine learning models for the identification of prognostic and predictive cancer biomarkers: a systematic review

Q Al-Tashi, MB Saad, A Muneer, R Qureshi… - International journal of …, 2023 - mdpi.com
The identification of biomarkers plays a crucial role in personalized medicine, both in the
clinical and research settings. However, the contrast between predictive and prognostic …

[HTML][HTML] Artificial intelligence-assisted dermatology diagnosis: from unimodal to multimodal

N Luo, X Zhong, L Su, Z Cheng, W Ma, P Hao - Computers in Biology and …, 2023 - Elsevier
Artificial Intelligence (AI) is progressively permeating medicine, notably in the realm of
assisted diagnosis. However, the traditional unimodal AI models, reliant on large volumes of …

[HTML][HTML] Deep learning in computational dermatopathology of melanoma: A technical systematic literature review

D Sauter, G Lodde, F Nensa, D Schadendorf… - Computers in biology …, 2023 - Elsevier
Deep learning (DL) has become one of the major approaches in computational
dermatopathology, evidenced by a significant increase in this topic in the current literature …

Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno‐Oncology Biomarker Working Group …

DB Page, G Broeckx, CA Jahangir… - The Journal of …, 2023 - Wiley Online Library
Modern histologic imaging platforms coupled with machine learning methods have provided
new opportunities to map the spatial distribution of immune cells in the tumor …

Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma …

E Chatziioannou, J Roßner, TN Aung, DL Rimm… - …, 2023 - thelancet.com
Background Recent advances in digital pathology have enabled accurate and standardised
enumeration of tumour-infiltrating lymphocytes (TILs). Here, we aim to evaluate TILs as a …

The challenging melanoma landscape: From early drug discovery to clinical approval

M Matias, JO Pinho, MJ Penetra, G Campos, CP Reis… - Cells, 2021 - mdpi.com
Melanoma is recognized as the most dangerous type of skin cancer, with high mortality and
resistance to currently used treatments. To overcome the limitations of the available …

Multiplexed immunohistochemistry and digital pathology as the foundation for next-generation pathology in melanoma: methodological comparison and future clinical …

Y Van Herck, A Antoranz, MD Andhari, G Milli… - Frontiers in …, 2021 - frontiersin.org
The state-of-the-art for melanoma treatment has recently witnessed an enormous revolution,
evolving from a chemotherapeutic,“one-drug-for-all” approach, to a tailored molecular-and …

Development of an image analysis-based prognosis score using Google's teachable machine in melanoma

S Forchhammer, A Abu-Ghazaleh, G Metzler, C Garbe… - Cancers, 2022 - mdpi.com
Simple Summary The increase in adjuvant treatment of melanoma patients makes it
necessary to provide the most accurate prognostic assessment possible, even at early …

Deep learning for skin melanocytic tumors in whole-slide images: A systematic review

A Mosquera-Zamudio, L Launet, Z Tabatabaei… - Cancers, 2022 - mdpi.com
Simple Summary Deep learning (DL) is expanding into the surgical pathology field and
shows promising outcomes in diminishing subjective interpretations, especially in …

Cancer immune exclusion: breaking the barricade for a successful immunotherapy

S Bruni, MF Mercogliano, FL Mauro… - Frontiers in …, 2023 - frontiersin.org
Immunotherapy has changed the course of cancer treatment. The initial steps were made
through tumor-specific antibodies that guided the setup of an antitumor immune response. A …