Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …

Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …

Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

The intestinal epithelium represents the most regenerative tissue in the human body, located
in proximity to the dense and functionally diverse microbial milieu of the microbiome …

The diet and gut microbiota have been extensively interrogated as a fuel for gut
inflammation in inflammatory bowel diseases (IBDs) in the last few years. Here, we review …

Paneth cells are versatile secretory cells located in the crypts of Lieberkühn of the small
intestine. In normal conditions, they function as the cornerstones of intestinal health by …

The intestinal barrier is a precisely regulated semi-permeable physiological structure that
absorbs nutrients and protects the internal environment from infiltration of pathological …

We are entering an era of medicine where increasingly sophisticated data will be obtained
from patients to determine proper diagnosis, predict outcomes and direct therapies. We …