Input function and modeling for determining bone metabolic flux using [18F] sodium fluoride PET imaging: A step‐by‐step guide

T Puri, ML Frost, AEB Moore, GJR Cook… - Medical …, 2023 - Wiley Online Library
Studies of skeletal metabolism using measurements of bone metabolic flux (Ki) obtained
with [18F] sodium fluoride ([18F] NaF) positron emission tomography (PET) scans have been …

[18F] Sodium Fluoride PET Kinetic Parameters in Bone Imaging

T Puri, ML Frost, GJ Cook, GM Blake - Tomography, 2021 - mdpi.com
This report describes the significance of the kinetic parameters (k-values) obtained from the
analysis of dynamic positron emission tomography (PET) scans using the Hawkins model …

Physical performance of adaptive axial FOV PET scanners with a sparse detector block rings or a checkerboard configuration

NA Karakatsanis, MH Nehmeh, M Conti… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. Using Monte-Carlo simulations, we evaluated the physical performance of a
hypothetical state-of-the-art clinical PET scanner with adaptive axial field-of-view (AFOV) …

Imaging of site specific bone turnover in osteoporosis using positron emission tomography

GM Blake, M Siddique, ML Frost, AEB Moore… - Current osteoporosis …, 2014 - Springer
The functional imaging technique of dynamic fluorine-18 labeled sodium fluoride positron
emission tomography (18 F-NaF PET) allows the quantitative assessment of regional bone …

Is response assessment of breast cancer bone metastases better with measurement of 18F-fluoride metabolic flux than with measurement of 18F-fluoride PET/CT SUV …

GK Azad, M Siddique, B Taylor, A Green… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Our purpose was to establish whether noninvasive measurement of changes in 18F-fluoride
metabolic flux to bone mineral (Ki) by PET/CT can provide incremental value in response …

[HTML][HTML] Site specific measurements of bone formation using [18F] sodium fluoride PET/CT

GM Blake, T Puri, M Siddique, ML Frost… - … imaging in medicine …, 2018 - ncbi.nlm.nih.gov
Dynamic positron emission tomography (PET) imaging with fluorine-18 labelled sodium
fluoride ([18 F] NaF) allows the quantitative assessment of regional bone formation by …

A semipopulation input function for quantifying static and dynamic 18F-fluoride PET scans

GM Blake, M Siddique, T Puri, ML Frost… - Nuclear medicine …, 2012 - journals.lww.com
Purpose We describe a semipopulation input function for evaluating bone plasma clearance
from static and dynamic 18 F-fluoride PET scans. Methods The semipopulation input …

Bone turnover prediction in patients with chronic kidney disease (CKD) undergoing hemodialysis using shortened dynamic 18F-NaF PET/CT Ki–Patlak

V Sanoesan, J Phannajit, K Kingpetch… - Scientific Reports, 2024 - nature.com
This study investigated whether Ki–Patlak derived from a shortened scan time for dynamic
18F-NaF PET/CT in chronic kidney disease (CKD) patients undergoing hemodialysis can …

Differences in regional bone metabolism at the spine and hip: a quantitative study using 18F-fluoride positron emission tomography

T Puri, ML Frost, KM Curran, M Siddique… - Osteoporosis …, 2013 - Springer
This study showed that regional bone blood flow and 18 F-fluoride bone plasma clearance
measured by positron emission tomography are three times lower at the hip than the lumbar …

[18F]Fluoromisonidazole PET in rectal cancer

T Puri, TA Greenhalgh, JM Wilson, J Franklin… - EJNMMI research, 2017 - Springer
Background There is an increasing interest in developing predictive biomarkers of tissue
hypoxia using functional imaging for personalised radiotherapy in patients with rectal cancer …