The multidisciplinary approach to Alzheimer's disease and dementia. A narrative review of non-pharmacological treatment

C Zucchella, E Sinforiani, S Tamburin… - Frontiers in …, 2018 - frontiersin.org
Background: Alzheimer's disease (AD) and dementia are chronic diseases with progressive
deterioration of cognition, function, and behavior leading to severe disability and death. The …

Aducanumab: appropriate use recommendations

J Cummings, P Aisen, LG Apostolova, A Atri… - The journal of …, 2021 - Springer
Aducanumab has been approved by the US Food and Drug Administration for treatment of
Alzheimer's disease (AD). Clinicians require guidance on the appropriate use of this new …

Digital endpoints in clinical trials of Alzheimer's disease and other neurodegenerative diseases: challenges and opportunities

AK Brem, S Kuruppu, C de Boer, M Muurling… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease (AD) and other neurodegenerative diseases such as Parkinson's
disease (PD) and Huntington's disease (HD) are associated with progressive cognitive …

Altered directed functional connectivity of the hippocampus in mild cognitive impairment and Alzheimer's disease: a resting-state fMRI study

J Xue, H Guo, Y Gao, X Wang, H Cui, Z Chen… - Frontiers in aging …, 2019 - frontiersin.org
The hippocampus is generally reported as one of the regions most impacted by Alzheimer's
disease (AD) and is closely associated with memory function and orientation. Undirected …

[HTML][HTML] Detecting functional decline from normal aging to dementia: development and validation of a short version of the Amsterdam IADL Questionnaire

RJ Jutten, CFW Peeters, SMJ Leijdesdorff… - Alzheimer's & Dementia …, 2017 - Elsevier
Introduction Detecting functional decline from normal aging to dementia is relevant for
diagnostic and prognostic purposes. Therefore, the Amsterdam IADL Questionnaire (A-IADL …

Psychometric properties of the Clinical Dementia Rating—Sum of Boxes and other cognitive and functional outcomes in a prodromal Alzheimer's disease population

F McDougall, C Edgar, M Mertes, P Delmar… - The Journal of …, 2021 - Springer
Abstract Background The Clinical Dementia Rating-Sum of Boxes (CDR-SB) has been
proposed as a primary outcome for use in prodromal AD trials. However, the psychometric …

[HTML][HTML] Impairment in complex activities of daily living is related to neurodegeneration in Alzheimer's disease–specific regions

RJ Jutten, E Dicks, L Vermaat, F Barkhof… - Neurobiology of …, 2019 - Elsevier
Impairment in instrumental activities of daily living (IADL) is an early clinical feature of
Alzheimer's disease (AD). The neurobiology underlying IADL disruptions is still unclear. We …

Dynamic complexity of spontaneous bold activity in Alzheimer's disease and mild cognitive impairment using multiscale entropy analysis

Y Niu, B Wang, M Zhou, J Xue, H Shapour… - Frontiers in …, 2018 - frontiersin.org
Alzheimer's disease (AD) is characterized by progressive deterioration of brain function
among elderly people. Studies revealed aberrant correlations in spontaneous blood oxygen …

Asociación entre el estado nutricional según índice de masa corporal y deterioro cognitivo en adultos mayores del Centro Médico Naval del Perú, 2010-2015

L Bazalar-Silva, FM Runzer-Colmenares… - Acta Médica …, 2019 - scielo.org.pe
Resumen BAZALAR-SILVA, Lorena; RUNZER-COLMENARES, Fernando M y PARODI,
José F. Asociación entre el estado nutricional según índice de masa corporal y deterioro …

The Cognitive‐Functional Composite is sensitive to clinical progression in early dementia: longitudinal findings from the Catch‐Cog study cohort

RJ Jutten, JE Harrison, AJ Brunner… - … Research & Clinical …, 2020 - Wiley Online Library
Introduction In an attempt to capture clinically meaningful cognitive decline in early
dementia, we developed the Cognitive‐Functional Composite (CFC). We investigated the …