Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Since the discovery of magainins, cecropins and defensins 30 years ago, antimicrobial
peptides (AMPs) have been hailed as a potential solution to the dearth of novel antibiotic …

Antimicrobial peptides (AMPs) are emerging as a promising alternative to traditional
antibiotics due to their ability to disturb bacterial membranes and/or their intracellular …

Antimicrobial peptides (AMPs) are the arsenals of the innate host defense system, exhibiting
evolutionarily conserved characteristics that are present in practically all forms of life. Recent …

Antimicrobial peptides (AMPs) attack bacterial membranes selectively, killing microbes at
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …

Melittin is a good model antimicrobial peptide to understand the basis of its lytic activities
against bacteria and mammalian cells. Novel analogues of melittin were designed by …

Due to the emergence of reports of multidrug-resistant fungi, infections caused by multidrug-
resistant fungi and biofilms are considered to be a global threat to human health due to the …

Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by
the pharmaceutical industry. These molecules are currently being used in the development …

To design novel antimicrobial peptides by utilizing the sequence of the human host defense
protein, chemerin, a seven-residue amphipathic stretch located in the amino acid region …

Indiscriminate use of antibiotics has led to a rapid increase of antibiotic resistance among
microbes which has increased the need to develop novel antimicrobial agents to fight …