The innate immune system relies on its capacity to rapidly detect invading pathogenic
microbes as foreign and to eliminate them. The discovery of Toll-like receptors (TLRs) …

Human IL-1 family proteins are key mediators of the host response to infections, injury, and
immunologic challenges. The mechanism by which IL-1 activates proinflammatory …

Antimicrobial peptides, which have been isolated from many bacteria, fungi, plants,
invertebrates and vertebrates, are an important component of the natural defenses of most …

Antimicrobial peptides are a vital component of the innate immune system of all eukaryotic
organisms and many of these peptides have potent antifungal activity. They have potential …

Objectives: The aim of this study was to investigate the mechanism of action of tea tree oil
and its components against Candida albicans, Candida glabrata and Saccharomyces …

The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

All organisms need protection against microorganisms, eg bacteria, viruses and fungi. For
many years, attention has been focused on adaptive immunity as the main antimicrobial …

Fungi have been used since ancient times in food and beverage-making processes and,
more recently, have been harnessed for the production of antibiotics and in processes of …

Dendritic cells (DCs) are professional antigen-presenting cells that initiate the immune
response by activating T lymphocytes. DCs express plasma membrane receptors for …

Following the widespread use of immunosuppressive therapy and broad-spectrum
antimycotic prophylaxis, C. glabrata has emerged as an important opportunistic pathogen in …