Oxidative stress and inflammation in diabetic nephropathy: role of polyphenols

Q Jin, T Liu, Y Qiao, D Liu, L Yang, H Mao… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress
demonstrates a crucial act in the onset and progression of DN, which triggers various …

[HTML][HTML] Recent developments in the role of protocatechuic acid in neurodegenerative disorders

R Thapa, A Goyal, G Gupta, AA Bhat, SK Singh… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Neurodegenerative disorders are chronic conditions characterized by the progressive and
consistent loss of nerve cells in the brain and spinal cord. Diseases like Alzheimer's …

Neuropharmacological effect of risperidone: From chemistry to medicine

AA Bhat, G Gupta, O Afzal, I Kazmi, FA Al-Abbasi… - Chemico-biological …, 2023 - Elsevier
As the second-oldest atypical antipsychotic, risperidone has a long history of off-label usage
for treating behavioural and psychological signs and symptoms of dementia (BPSD), such …

Plants as a source of anticancer agents: From bench to bedside

WH Talib, S Daoud, AI Mahmod, RA Hamed, D Awajan… - Molecules, 2022 - mdpi.com
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …

Chronic atrophic gastritis: a review

Y Li, R Xia, B Zhang, C Li - Journal of Environmental Pathology …, 2018 - dl.begellhouse.com
Chronic atrophic gastritis is a generally asymptomatic condition of great importance because
it develops into gastric cancer in a number of patients. It is described as an atrophy of the …

[HTML][HTML] Molecular modulators of celastrol as the keystones for its diverse pharmacological activities

SW Ng, Y Chan, DK Chellappan… - Biomedicine & …, 2019 - Elsevier
In the recent years, much attention has been focused on identifying bioactive compounds
from medicinal plants that could be employed in therapeutics, which is attributed to their …

Luteolin attenuates diabetic nephropathy through suppressing inflammatory response and oxidative stress by inhibiting STAT3 pathway

M Zhang, L He, J Liu, L Zhou - Experimental and Clinical …, 2021 - thieme-connect.com
Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease
(ESRD). DN has many pathological changes, but tubular injury is considered to be a crucial …

Luteolin attenuates glucocorticoid‐induced osteoporosis by regulating ERK/Lrp‐5/GSK‐3β signaling pathway in vivo and in vitro

Z Jing, C Wang, Q Yang, X Wei, Y Jin… - Journal of cellular …, 2019 - Wiley Online Library
Glucocorticoid‐induced osteoporosis (GIO) is a secondary osteoporosis with extensive use
of glucocorticoids (GCs). GCs can increase bone fragility and fracture via inhibiting …

Lysozyme–luteolin binding: molecular insights into the complexation process and the inhibitory effects of luteolin towards protein modification

S Das, S Pahari, S Sarmah, MA Rohman… - Physical Chemistry …, 2019 - pubs.rsc.org
In the proposed work, the complexation of bioactive flavonoid luteolin with hen egg white
lysozyme (HEWL) along with its inhibitory influence on HEWL modification has been …

Protective role of luteolin against bisphenol A‐induced renal toxicity through suppressing oxidative stress, inflammation, and upregulating Nrf2/ARE/HO‐1 pathway

GJ Alekhya Sita, M Gowthami, G Srikanth… - IUBMB …, 2019 - Wiley Online Library
For the development of renal diseases, oxidative stress (OS) is reasoned to be one of the
risk factors. For the treatment or prevention of the renal disease, the use of antioxidants …