Mechanisms contributing to prefrontal cortex maturation during adolescence

A Caballero, R Granberg, KY Tseng - Neuroscience & Biobehavioral …, 2016 - Elsevier
Adolescence is defined as a transitional period between childhood and adulthood
characterized by changes in social interaction and acquisition of mature cognitive abilities …

GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder

FM Benes, S Berretta - Neuropsychopharmacology, 2001 - Elsevier
A core component to corticolimbic circuitry is the GABAergic interneuron. Neuroanatomic
studies conducted over the past century have demonstrated several subtypes of interneuron …

Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction

PS Goldman-Rakic, SA Castner, TH Svensson… - …, 2004 - Springer
Background and rationale Reinstatement of the function of working memory, the cardinal
cognitive process essential for human reasoning and judgment, is potentially the most …

Norepinephrine versus dopamine and their interaction in modulating synaptic function in the prefrontal cortex

B Xing, YC Li, WJ Gao - Brain research, 2016 - Elsevier
Among the neuromodulators that regulate prefrontal cortical circuit function, the
catecholamine transmitters norepinephrine (NE) and dopamine (DA) stand out as powerful …

Neurological bases for balance–anxiety links

CD Balaban, JF Thayer - Journal of anxiety disorders, 2001 - Elsevier
This review paper examines neurologic bases of links between balance control and anxiety
based upon neural circuits that are shared by pathways that mediate autonomic control …

Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery

DS Goldwater, C Pavlides, RG Hunter, EB Bloss… - Neuroscience, 2009 - Elsevier
Chronic stress has been shown in animal models to result in altered dendritic morphology of
pyramidal neurons of the medial prefrontal cortex (mPFC). It has been hypothesized that the …

Pharmacology and behavioral pharmacology of the mesocortical dopamine system

TM Tzschentke - Progress in neurobiology, 2001 - Elsevier
The prefrontal cortex (PFC) has long been known to be involved in the mediation of complex
behavioral responses. Considerable research efforts are directed towards refining the …

The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia

KY Tseng, RA Chambers, BK Lipska - Behavioural brain research, 2009 - Elsevier
Traditionally, animal models of schizophrenia were predominantly pharmacological
constructs focused on phenomena linked to dopamine and glutamate neurotransmitter …

Monoaminergic neuromodulation of sensory processing

SN Jacob, H Nienborg - Frontiers in neural circuits, 2018 - frontiersin.org
All neuronal circuits are subject to neuromodulation. Modulatory effects on neuronal
processing and resulting behavioral changes are most commonly reported for higher order …

Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting

SB Floresco, O Magyar, S Ghods-Sharifi… - …, 2006 - nature.com
Dopamine (DA) input to the prefrontal cortex (PFC), acting on D1 receptors, plays an
essential role in mediating working memory functions. In comparison, less is known about …