Health implications of high dietary omega‐6 polyunsaturated fatty acids

E Patterson, R Wall, GF Fitzgerald… - Journal of nutrition …, 2012 - Wiley Online Library
Omega‐6 (n‐6) polyunsaturated fatty acids (PUFA)(eg, arachidonic acid (AA)) and omega‐3
(n‐3) PUFA (eg, eicosapentaenoic acid (EPA)) are precursors to potent lipid mediator …

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

G Musso, R Gambino, M Cassader - Progress in lipid research, 2009 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in
Western countries and is considered the hepatic manifestation of metabolic syndrome. The …

Nutritional intervention with fish oil provides a benefit over standard of care for weight and skeletal muscle mass in patients with nonsmall cell lung cancer receiving …

RA Murphy, M Mourtzakis, QSC Chu, VE Baracos… - Cancer, 2011 - Wiley Online Library
BACKGROUND: Involuntary weight loss is a major contributor to mortality and morbidity in
patients with advanced cancer. Nutritional intervention with fish oil (FO)‐derived …

[HTML][HTML] (n-3) Fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights

NS Kalupahana, KJ Claycombe… - Advances in nutrition, 2011 - Elsevier
Obesity is associated with the metabolic syndrome, a significant risk factor for developing
type 2 diabetes and cardiovascular diseases. Chronic low-grade inflammation occurring in …

Oryzanol modifies high fat diet-induced obesity, liver gene expression profile, and inflammation response in mice

L Wang, Q Lin, T Yang, Y Liang, Y Nie… - Journal of agricultural …, 2017 - ACS Publications
In Western countries and China, the dietary habit of high calories usually results in
hyperlipidemia, which is closely associated with cardiovascular diseases. In the study, we …

Hormonal and nutritional regulation of SCD1 gene expression

D Mauvoisin, C Mounier - Biochimie, 2011 - Elsevier
Stearoyl-CoA Desaturase 1 (SCD1) is the rate limiting enzyme catalyzing the biosynthesis of
monounsaturated fatty acids preferentially from palmitoyl-CoA and stearoyl-CoA forming …

Nutritional investigation of non-obese patients with non-alcoholic fatty liver disease: the significance of dietary cholesterol

K Yasutake, M Nakamuta, Y Shima… - Scandinavian journal …, 2009 - Taylor & Francis
Objective. The onset and progression of non-alcoholic fatty liver disease (NAFLD) seem to
be affected by nutritive intake; however, detailed examinations have not been performed in …

[HTML][HTML] Dietary habits and behaviors associated with nonalcoholic fatty liver disease

K Yasutake, M Kohjima, K Kotoh… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent causes of health
problems in Western (industrialized) countries. Moreover, the incidence of infantile NAFLD is …

The lipogenesis pathway as a cancer target

HN Abramson - Journal of medicinal chemistry, 2011 - ACS Publications
Lipids constitute some of nature's most abundant molecules, being found in virtually all
forms of life. They are derived by condensation reactions involving acetate units and may be …

Omega 3–Omega 6: What is right for the liver?

AM El-Badry, R Graf, PA Clavien - Journal of hepatology, 2007 - Elsevier
Linoleic and α-linolenic acids are the fatty acids designated as “essential” since they are not
synthesized by mammalian cells and must be provided in the diet. The recent dietary shift …