Background: Cancer is a disease characterized by uncontrolled cell growth and
proliferation. It has become a major health problem in the past decades and is now the …

Throughout history, natural products have afforded a rich source of compounds that have
found many applications in the fields of medicine, pharmacy and biology. Within the sphere …

Abstract A 4-component antibody-phthalocyanine-polyethylene glycol-gold nanoparticle
conjugate is described for use as a potential drug for targeted photodynamic cancer therapy …

Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

This review provides an overview of the discovery, structures, and biological activities of
anticancer natural products that act by inhibiting or promoting the assembly of tubulin to …

Natural products have made significant contribution to cancer chemotherapy over the past
decades and remain an indispensable source of molecular and mechanistic diversity for …

The importance of microtubules in mitosis makes them a superb target for a group of highly
successful, chemically diverse anticancer drugs. Knowledge of the mechanistic differences …

Photodynamic therapy (PDT) is a treatment of cancer by which tumour cells are destroyed
using reactive oxygen species produced by photosensitizers following activation with visible …

ABSTRACT Background Neratinib (HKI-272) is a potent irreversible pan-ErbB tyrosine
kinase inhibitor with clinical activity in patients with ErbB2/HER2-positive breast cancer …

This article reports on recent advances on metastatic breast cancer. Detection, prognostic
factors, predictors of response to therapy and therapy, with particular regard to targeted …