OXA-48-like β-lactamases: global epidemiology, treatment options, and development pipeline

SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Understanding the epidemiology of multi-drug resistant gram-negative bacilli in the Middle East using a one health approach

I Dandachi, A Chaddad, J Hanna, J Matta… - Frontiers in …, 2019 - frontiersin.org
In the last decade, extended-spectrum cephalosporin and carbapenem resistant Gram-
negative bacilli (GNB) have been extensively reported in the literature as being …

Extended spectrum-and carbapenemase-based β-lactam resistance in the arabian peninsula—a descriptive review of recent years

JP Hays, KS Safain, MS Almogbel, I Habib, MA Khan - Antibiotics, 2022 - mdpi.com
Antimicrobial resistance (AMR) is a global problem that also includes countries of the
Arabian Peninsula. Of particular concern, is the continuing development of extended …

[HTML][HTML] Prevalence and molecular epidemiology of carbapenem-resistant Gram-negative bacilli and their resistance determinants in the Eastern Mediterranean …

A Sleiman, AG Abou Fayad, H Banna… - Journal of Global …, 2021 - Elsevier
Abstract Carbapenem resistance in Enterobacteriaceae, Acinetobacter baumannii, and
Pseudomonas aeruginosa is increasing worldwide, which led the WHO to list these bacteria …

[HTML][HTML] Emergence of mcr-1 gene and carbapenemase-encoding genes among colistin-resistant Klebsiella pneumoniae clinical isolates in Jordan

MH Gharaibeh, DA Alyafawi, ZA Elnasser… - Journal of Infection and …, 2022 - Elsevier
Background Antimicrobial resistance (AMR) is a global threat that requires serious attention,
particularly when it is developed against colistin, which is considered one of the 'last …

Resistance to aminoglycoside and quinolone drugs among Klebsiella pneumoniae clinical isolates from northern Jordan

S Swedan, EA Alabdallah, Q Ababneh - Heliyon, 2024 - cell.com
This study aimed to identify phenotypic and genotypic aminoglycoside and quinolone non-
susceptibility and the prevalence of aminoglycoside-modifying enzymes and plasmid …

Epidemiology of carbapenemase-producing Enterobacterales in the Middle East: a systematic review

A Touati, A Mairi - Expert Review of Anti-infective Therapy, 2020 - Taylor & Francis
ABSTRACT Introduction The Middle East is actually recognized as endemic for
carbapenemases-producing Enterobacterales (CPE) including at least OXA-48-like and …

[HTML][HTML] Phenotypic and genotypic characterisation of cephalosporin-, carbapenem-and colistin-resistant Gram-negative bacterial pathogens in Lebanon, Jordan and …

RA Moghnieh, JA Moussa, MA Aziz… - Journal of global …, 2021 - Elsevier
Antimicrobial resistance (AMR) is a worldwide health concern that continues to escalate. A
PubMed literature search identified articles from January 2015–August 2020 reviewing …

Characterization of carbapenem-resistant Enterobacteriaceae clinical isolates in al thawra university hospital, Sana'a, Yemen

SA Alsharapy, A Gharout-Sait, A Muggeo… - Microbial Drug …, 2020 - liebertpub.com
Objective: The aim of this study was to investigate the resistance mechanisms of
carbapenem-resistant Enterobacteriaceae clinical strains recovered from Al Thawra …

Cefixime and cefixime-clavulanate for screening and confirmation of extended-spectrum beta-lactamases in Escherichia coli

M Al-Tamimi, H Albalawi, M Shalabi… - Annals of Clinical …, 2022 - Springer
Abstract Introduction Detection of Extended-Spectrum Beta-Lactamases (ESBLs) depends
on screening for resistance to certain cephalosporins, confirmation with selective ESBL …