Lichen secondary metabolites have tremendous pharmaceutical and industrial potential.
Although more than 1000 metabolites have been reported from lichens, less than 10 have …

Several research studies have shown that lichens are productive organisms for the
synthesis of a broad range of secondary metabolites. Lichens are a self-sustainable stable …

Depsides are polyphenolic molecules comprising two or more phenolic acid derivatives
linked by an ester bond, which is called a depside bond in these molecules. Despite more …

Fungi produce a vast number of secondary metabolites that shape their interactions with
other organisms and the environment. Characterizing the genes underpinning metabolite …

Primary biosynthetic enzymes involved in the synthesis of lichen polyphenolic compounds
depsides and depsidones are non-reducing polyketide synthases (NR-PKSs), and …

Fungal aromatic prenyltransferases are a family of biosynthetic enzymes that catalyze the
prenylation of a range of aromatic substrates during the biosynthesis of bioactive indole …

Lichen natural products are a tremendous source of new bioactive chemical entities for drug
discovery. The ability to survive in harsh conditions can be directly correlated with the …

Fungi involved in lichen symbioses produce a large array of secondary metabolites that are
often diagnostic in the taxonomic delimitation of lichens. The most common lichen …

Thielavin A (1) is a fungal depside composed of one 3‐methylorsellinic acid and two 3, 5‐
dimethylorsellinic acid units. It displays diverse biological activities. However, the …

Lichenized fungi are known for their production of a diversity of secondary metabolites,
many of which have broad biological and pharmacological applications. By far the most well …