Validated biomarkers for patients suffering from gliomas are urgently needed for
standardizing measurements of the effects of treatment in daily clinical practice and trials …

Background Glioblastoma (GBM) is the most common and aggressive primary malignant
brain tumor. Leptomeningeal spread (LMS) is a severe complication of GBM, raising …

Background This presentation of two cases and literature review discusses the
epidemiology, clinical manifestations, pathogenesis, diagnosis, treatment, and prognosis of …

Introduction Glioblastoma is an aggressive cancer with a notoriously poor prognosis. Recent
advances in treatment have increased overall survival, though this may be accompanied by …

Leptomeningeal metastasis (LM) of high grade gliomas (HGG) can lead to devastating
disease courses. Understanding of risk factors for LM is important to identify patients at risk …

Glioblastoma (GBM) is one of the most highly aggressive neoplasms of the central nervous
system. Extra-cranial metastases in GBM are rare. Here we present the case of a 26-year …

A 17-year-old girl with World Health Organization grade IV glioblastoma with primitive
neuronal components (histone H3 G34-mutant and IDH1 wild type) underwent whole-body …

We present a 59-year-old woman who noted an enlarging lump on her forehead 6 months
after a left frontotemporal craniotomy for tumor resection and chemoradiation of her primary …

OBJECTIVE Spinal metastases from primary intracranial glioblastoma (GBM) are
infrequently reported, and the disease has yet to be well characterized. A more accurate …

Purpose Glioblastoma (GBM) that presents as leptomeningeal disease (LMD) is extremely
rare and fatal. Limited data are available regarding incidence, clinical presentation, and …