Choline, neurological development and brain function: a systematic review focusing on the first 1000 days
E Derbyshire, R Obeid - Nutrients, 2020 - mdpi.com
The foundations of neurodevelopment across an individual's lifespan are established in the
first 1000 days of life (2 years). During this period an adequate supply of nutrients are …
first 1000 days of life (2 years). During this period an adequate supply of nutrients are …
A systematic review of the dietary choline impact on cognition from a psychobiological approach: Insights from animal studies
The influence of dietary choline availability on cognition is currently being suggested by
animal and human studies which have focused mainly on the early developmental stages …
animal and human studies which have focused mainly on the early developmental stages …
Adolescent choline supplementation attenuates working memory deficits in rats exposed to alcohol during the third trimester equivalent
RD Schneider, JD Thomas - Alcoholism: Clinical and …, 2016 - Wiley Online Library
Background Children exposed to alcohol prenatally may suffer from behavioral and
cognitive alterations that adversely affect their quality of life. Animal studies have shown that …
cognitive alterations that adversely affect their quality of life. Animal studies have shown that …
Perinatal choline supplementation reduces amyloidosis and increases choline acetyltransferase expression in the hippocampus of the APPswePS1dE9 Alzheimer's …
TJ Mellott, OM Huleatt, BN Shade, SM Pender, YB Liu… - PloS one, 2017 - journals.plos.org
Prevention of Alzheimer's disease (AD) is a major goal of biomedical sciences. In previous
studies we showed that high intake of the essential nutrient, choline, during gestation …
studies we showed that high intake of the essential nutrient, choline, during gestation …
Dietary choline supplementation to dams during pregnancy and lactation mitigates the effects of in utero stress exposure on adult anxiety-related behaviors
KM Schulz, JN Pearson, ME Gasparrini… - Behavioural brain …, 2014 - Elsevier
Brain cholinergic dysfunction is associated with neuropsychiatric illnesses such as
depression, anxiety, and schizophrenia. Maternal stress exposure is associated with these …
depression, anxiety, and schizophrenia. Maternal stress exposure is associated with these …
Choline ameliorates adult learning deficits and reverses epigenetic modification of chromatin remodeling factors related to adolescent nicotine exposure
Earlier initiation of smoking correlates with higher risk of nicotine dependence, mental health
problems, and cognitive impairments. Additionally, exposure to nicotine and/or tobacco …
problems, and cognitive impairments. Additionally, exposure to nicotine and/or tobacco …
[HTML][HTML] Choline Supplementation in Pregnancy: Current Evidence and Implications
A Jaiswal, D Dewani, LS Reddy, A Patel - Cureus, 2023 - ncbi.nlm.nih.gov
Choline, an essential nutrient, is pivotal in supporting maternal and fetal health during
pregnancy. In this comprehensive review, we explore the current evidence and the …
pregnancy. In this comprehensive review, we explore the current evidence and the …
CDP-choline: Effects of the procholine supplement on sensory gating and executive function in healthy volunteers stratified for low, medium and high P50 suppression
V Knott, D Smith, S de la Salle… - Journal of …, 2014 - journals.sagepub.com
Diminished auditory sensory gating and associated neurocognitive deficits in schizophrenia
have been linked to altered expression and function of the alpha-7 nicotinic acetycholinergic …
have been linked to altered expression and function of the alpha-7 nicotinic acetycholinergic …
Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice
KE Stevens, KS Choo, JA Stitzel, MJ Marks, CE Adams - Brain research, 2014 - Elsevier
Perinatal choline supplementation has produced several benefits in rodent models, from
improved learning and memory to protection from the behavioral effects of fetal alcohol …
improved learning and memory to protection from the behavioral effects of fetal alcohol …
An acute dose, randomized trial of the effects of CDP-Choline on Mismatch Negativity (MMN) in healthy volunteers stratified by deviance detection level
V Knott, D Impey, J Choueiry, D Smith… - Neuropsychiatric …, 2015 - Springer
Background Alpha 7 nicotinic acetylcholine receptors (α7 nAChR) are prioritized molecular
targets for the development of new pharmacological treatments for impaired cognition in …
targets for the development of new pharmacological treatments for impaired cognition in …