Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies

M Bertolini, MS Wong, L Mendive-Tapia… - Chemical Society …, 2023 - pubs.rsc.org
T cells are an essential part of the immune system with crucial roles in adaptive response
and the maintenance of tissue homeostasis. Depending on their microenvironment, T cells …

Dithio-fused boron dipyrromethenes: synthesis and impact of S-heteroaromatic annulation mode

J Li, N Xue, S Gao, Y Yang, Z Weng, H Ju… - Organic …, 2024 - ACS Publications
Three dithio-fused boron dipyrromethenes (BODIPYs), DTFB-1, DTFB-2, and DTFB-3, in
which symmetrically S-heteroaromatic ring units fused at [a], zigzag, and [b] bonds of the …

Inserting “OFF-to-ON” BODIPY tags into cytokines: a fluorogenic interleukin IL-33 for real-time imaging of immune cells

AE Reese, F de Moliner, L Mendive-Tapia… - ACS Central …, 2023 - ACS Publications
The essential functions that cytokine/immune cell interactions play in tissue homeostasis
and during disease have prompted the molecular design of targeted fluorophores to monitor …

[HTML][HTML] Recent advances in minimal fluorescent probes for optical imaging

F De Moliner, F Nadal-Bufi, M Vendrell - Current opinion in chemical …, 2024 - Elsevier
Fluorescent probes have revolutionized biological imaging by enabling the real-time
visualization of cellular processes under physiological conditions. However, their size and …

Chemo-Click: Receptor-Controlled and Bioorthogonal Chemokine Ligation for Real-Time Imaging of Drug-Resistant Leukemic B Cells

M Bertolini, L Mendive-Tapia, U Karmakar… - Journal of the …, 2024 - ACS Publications
Drug resistance in B cell leukemia is characterized by the coexpression of CXCR5 and
CXCR3 chemokine receptors, making it a valuable biomarker for patient stratification …

Access to isoindole-derived BODIPYs by an aminopalladation cascade

HF von Köller, FJ Geffers, P Kalvani, A Foraita… - Chemical …, 2023 - pubs.rsc.org
Here, we present a new route to dyes of the BODIPY family. We first built up a N-Boc-
protected dipyrromethene scaffold via an aminopalladation cascade. Subsequentially, the …

Alared: Solvatochromic and Fluorogenic Red Amino Acid for Ratiometric Live‐cell Imaging of Bioactive Peptides

A Mirloup, Y Berthomé, S Riché… - … A European Journal, 2024 - Wiley Online Library
To fill the need for environmentally sensitive fluorescent unnatural amino acids able to
operate in the red region of the spectrum, we have designed and synthesized Alared, a red …

No-wash fluorogenic labeling of proteins for reversible photoswitching in live cells

K Torii, S Benson, Y Hori, M Vendrell, K Kikuchi - Chemical Science, 2024 - pubs.rsc.org
Photoswitchable fluorescent molecules (PSFMs) are positioned as valuable tools for
biomolecule localization tracking and super-resolution imaging technologies due to their …

Recent Progress in Peptide-Based Molecular Probes for Disease Bioimaging

Y Xu, J Chen, Y Zhang, P Zhang - Biomacromolecules, 2024 - ACS Publications
Recent strides in molecular pathology have unveiled distinctive alterations at the molecular
level throughout the onset and progression of diseases. Enhancing the in vivo visualization …

Enhanced mitochondrial fluorescence imaging through confinement fluorescence effect within a rigid silicon suboxide network

Y Shen, B Fang, T Shao, J Zhang, H Li, L Wang… - Biosensors and …, 2025 - Elsevier
Fluorescence imaging technology has emerged as a powerful tool for studying intricate
mitochondrial morphology within living cells. However, the need for fluorophores with stable …