Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Cyclic cell-penetrating peptides are relatively a newer class of peptides that have a huge
potential for the intracellular delivery of therapeutic agents aimed at treating challenging …

Cancer is the second leading cause of death worldwide, and the search for specialised
therapy options has been a challenge for decades. The emergence of active targeted …

Much effort has been dedicated in the recent decades to find novel protein/enzyme-based
therapies for human diseases, the major challenge of such therapies being the intracellular …

Epstein–Barr virus (EBV) is a major contributor to nasopharyngeal carcinoma (NPC)
tumorigenesis. Mitochondria have been shown to be a target for tumor viral invasion, and to …

Cyclopeptides are ubiquitous scaffolds and could exert the anticancer effects through
diverse mechanisms, inclusive of induction of apoptosis and autophagy, antiangiogenesis …

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Cell-penetrating peptides (CPPs) are versatile tools to deliver various molecules into
different cell types. The majority of CPPs are usually represented by linear structures, but …

Using 2-chloro-trityl chloride resin as a solid phase carrier, a linear peptide was synthesized
by Fmoc solid phase synthesis followed by liquid phase cyclization. After separation and …

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