At the frontline of the host defence response, neutrophil antimicrobial functions have
adapted to combat infections and injuries of different origins and magnitude. The release of …

Neutrophil extracellular traps (NETs) evolved to protect the host against microbial infections
and are formed by a web-like structure of DNA that is decorated with antimicrobial effectors …

Neutrophils are innate immune phagocytes that have a central role in immune defence. Our
understanding of the role of neutrophils in pathogen clearance, immune regulation and …

Accumulation of lactate in the tissue microenvironment is a feature of both inflammatory
disease and cancer. Here, we assess the response of immune cells to lactate in the context …

Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are
renowned for their propensity to expel decondensed chromatin embedded with inflammatory …

Overactivated T cells and overproduced pro‐inflammatory cytokines form a self‐amplified
signaling loop to continuously exacerbate the dysregulated inflammatory response and …

Neutrophils, the most abundant circulating leukocyte, are critical for host defense.
Granulopoiesis is under the control of transcriptional factors and culminates in mature …

Neutrophils recognize particulate substrates of microbial or endogenous origin and react by
sequestering the cargo via phagocytosis or by releasing neutrophil extracellular traps …

Neutrophil extracellular traps (NETs) are characterized as extracellular DNA fibers
comprised of histone and cytoplasmic granule proteins. NETs were first described as a form …

Sepsis results in millions of deaths every year, with acute lung injury (ALI) being one of the
leading causes of mortality in septic patients. As neutrophil extracellular traps (NETs) are …