Background Several new targeted genes and clinical subtypes have been identified since
publication in 2008 of the report of the last international consensus meeting on diagnosis …

Desmosomes are intercellular junctions of epithelia and cardiac muscle. They resist
mechanical stress because they adopt a strongly adhesive state in which they are said to be …

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide.
We performed a genetic association study in 15,256 cases and 47,936 controls, with …

BACKGROUND: Since publication in 2000 of the Second International Consensus Report
on Diagnosis and Classification of Epidermolysis Bullosa, many advances have been made …

Desmosomes are intercellular junctions that tether intermediate filaments to the plasma
membrane. Desmogleins and desmocollins, members of the cadherin superfamily, mediate …

Based upon case reports and small case series, it has been known for many years that
some types and subtypes of inherited epidermolysis bullosa (EB) may be at risk for …

Written by two leaders in the field of pediatric dermatology, this classic text provides both
detailed content for the specialist and easily accessible information for the non …

Intercellular communication is essential for proper cardiac function. Mechanical and
electrical activity need to be synchronized so that the work of individual myocytes transforms …

Inherited epidermolysis bullosa (EB) encompasses a number of disorders characterized by
recurrent blister formation as the result of structural fragility within the skin and selected other …

Overview: Nails grow at the approximate rate of 1 mm each day. Fingernails take six months
to progress from the base to the end of the finger, and toenails take nine months to reach the …