Background Vascular complications are the leading cause of morbidity and mortality among
patients with type 1 and type 2 diabetes mellitus. These vascular abnormalities result of a …

The metabolic syndrome is a cluster of cardiometabolic alterations that include the presence
of arterial hypertension, insulin resistance, dyslipidemia, and abdominal obesity. Obesity is …

Rationale: As the mechanism that links obstructive sleep apnea (OSA) with the regulation of
inflammatory response is not well known, it is important to understand the inflammasome …

Periodontitis is a bacterium-induced chronic inflammation that destroys tissues that attach
teeth to jaw bone. Pathologically excessive matrix metalloproteinase 8 (MMP-8) is among …

Atherosclerosis is responsible for 20% of ischemic strokes, and the plaques from the internal
carotid artery the most frequently involved. Lipoproteins play a key role in carotid …

Atherosclerosis is now widely recognized as a chronic inflammatory disease that involves
innate and adaptive immune responses. Both cellular and humoral components of the …

Matrix metalloproteinases (MMPs) play a role in collagen breakdown, leading to plaque
instability. High levels of MMPs mRNA and proteins, especially MMP-1, MMP-2, MMP-8 …

Background Increased plasma D-dimer levels have been reported to be associated with a
range of adverse health outcomes. This study aimed to determine whether plasma D-dimer …

Aim To evaluate the clinical, microbiological and immunological effects of systemic
doxycycline as an adjunct to scaling and root planing (SRP) in chronic periodontitis patients …

There is compelling evidence indicating that some members of the matrix metalloproteinase
(MMP) family play important roles in the pathogenesis of atherosclerosis and related …