Unraveling the emerging niche role of extracellular vesicles (EVs) in traumatic brain injury (TBI)

S Ashique, R Pal, H Sharma, N Mishra… - CNS & Neurological …, 2024 - benthamdirect.com
Extracellular vesicles or exosomes, often known as EVs, have acquired significant attention
in the investigations of traumatic brain injury (TBI) and have a distinct advantage in actively …

[HTML][HTML] Extracellular vesicles: The next generation of biomarkers and treatment for central nervous system diseases

G Zanirati, PG Dos Santos, AM Alcará, F Bruzzo… - International Journal of …, 2024 - mdpi.com
It has been widely established that the characterization of extracellular vesicles (EVs),
particularly small EVs (sEVs), shed by different cell types into biofluids, helps to identify …

Extracellular vesicles from human‐induced pluripotent stem cell‐derived neural stem cells alleviate proinflammatory cascades within disease‐associated microglia in …

LN Madhu, M Kodali, R Upadhya, S Rao… - Journal of …, 2024 - Wiley Online Library
As current treatments for Alzheimer's disease (AD) lack disease‐modifying interventions,
novel therapies capable of restraining AD progression and maintaining better brain function …

Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis …

G Ayyubova, M Kodali, R Upadhya, LN Madhu… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) released by human induced pluripotent stem cell-derived neural
stem cells (hiPSC-NSCs) are enriched with miRNAs and proteins capable of mediating …

[HTML][HTML] FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and …

M Kodali, LN Madhu, VSV Kolla, S Attaluri… - Military Medical …, 2024 - Springer
Chronic Gulf War Illness (GWI) is characterized by cognitive and mood impairments, as well
as persistent neuroinflammation and oxidative stress. This study aimed to investigate the …

Extracellular vesicle therapy in neurological disorders

N Putthanbut, JY Lee, CV Borlongan - Journal of Biomedical Science, 2024 - Springer
Extracellular vesicles (EVs) are vital for cell-to-cell communication, transferring proteins,
lipids, and nucleic acids in various physiological and pathological processes. They play …

Emerging role and translational potential of small extracellular vesicles in neuroscience

I Shanmugam, S Radhakrishnan, S Santosh… - Life Sciences, 2024 - Elsevier
Small extracellular vesicles (sEV) are endogenous lipid-bound membrane vesicles secreted
by both prokaryotic and eukaryotic cells into the extracellular environment, performs several …

Magnetic particle imaging reveals that iron-labeled extracellular vesicles accumulate in brains of mice with metastases

VA Toomajian, A Tundo, EE Ural… - … Applied Materials & …, 2024 - ACS Publications
The incidence of breast cancer remains high worldwide and is associated with a significant
risk of metastasis to the brain that can be fatal; this is due, in part, to the inability of …

Intranasal delivery of extracellular vesicles: A promising new approach for treating neurological and respiratory disorders

SV Sánchez, GN Otavalo, F Gazeau, AKA Silva… - Journal of Controlled …, 2025 - Elsevier
Abstract Background Extracellular vesicles (EVs) are membrane vesicles secreted by all
types of cells, including bacteria, animals, and plants. These vesicles contain proteins …

Advances in neuronal regeneration: Hydrogel-based delivery systems loaded with extracellular vesicles in modulating neural impulses and tissue repair

P Pal, M Sharma, KS Bani, SK Gupta - European Polymer Journal, 2024 - Elsevier
This review explores the transformative potential of integrating hydrogel-based systems with
extracellular vesicles (EVs) in the field of neural regeneration. Hydrogels offer a …